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Introducing a noninvasive, non-surgical, and reversible animal model for fecal incontinence using abobotulinumtoxinA in dogs

Mohammad Yasan Bangash; Mir Sepehr Pedram; Valiollah Mehrabi; Mohammad Mehdi Dehghan; Koorosh Mansoori; Sarang Soroori; Sanaz Banifazl; Forough Dadgar; Mohammad Reza Mokhber Dezfouli

Volume 13, Issue 2 , June 2022, , Pages 215-221

Abstract
  The aim of this study was to introduce a new animal model of fecal incontinence (FI) by injecting abobotulinumtoxinA in the external anal sphincter (EAS) muscle of dogs which replaces models based on anal sphincter destructions that are invasive, mostly require surgical procedures, expensive, permanent, ...  Read More