%0 Journal Article %T Adenovirus-like inclusion body hepatitis in a flock of broiler chickens in Kermanshah province, Iran %J Veterinary Research Forum %I Faculty of Veterinary Medicine, Urmia University %Z 2008-8140 %A Rahimi, Morad %A Minoosh Siavosh Haghighi, Zahra %D 2015 %\ 03/01/2015 %V 6 %N 1 %P 95-98 %! Adenovirus-like inclusion body hepatitis in a flock of broiler chickens in Kermanshah province, Iran %K Adenovirus %K Broiler %K Hepatitis %K Inclusion body %K Iran %R %X Inclusion body hepatitis (IBH) has been reported in many countries in the world. The IBH or similar cases characterized by hepatitis and presence of intra-nuclear inclusion bodies in hepatocytes have not been reported in broiler chickens in Iran. This is the first report on outbreak of adenovirus-like inclusion body hepatitis in Iran. On October 2012, an onset of high acute mortality in a flock of 2 day-old broiler chickens was reported to the Veterinary Clinic, Faculty of Veterinary Medicine, Razi University, Kermanshah, Iran. The birds showed lethargy, huddling, ruffled feathers, and inappetence. At necropsy the livers were the primary organ affected which were enlarged, pale yellow with necrotic foci and multiple petechial hemorrhages. Tissue samples of liver, kidneys and heart were fixed in 10% buffered formalin. They were processed and stained with hematoxylin and eosin for histopathological studies. Significant microscopic lesions were seen in the livers. Large eosinophilic intra-nuclear inclusion bodies were seen in hepatocytes. Based on the acute high mortality, age of the broilers, gross lesions and histopathological findings (especially intra-nuclear inclusion bodies), the condition was diagnosed as adenovirus-like inclusion body hepatitis. %U https://vrf.iranjournals.ir/article_11347_463c787afaa2968e9e84dcc48b5cf785.pdf