Document Type : Short Communication
Department of Clinical Sciences. Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
Department of Small Animal Medicine &amp;amp; Radiology, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
Department of Clinical Science, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Department of Epidemiology, Veterinary Medicine Faculty, University of Tehran, Tehran, Iran.
The purpose of the present study is to evaluate effects of medetomidine on left ventricular outflow tract velocity in domestic short-haired cats. Eighteen healthy adult male domestic short-haired cats were used for this study. All animals were client owned. Echocardiography machine with 7.5 MHz tranducer was used. Specific veterinary Two-dimensional and pulse-waved echocardiogram images in apical five chamber right parasternal window were obtained and blood velocity in LVOT were calculated. After baseline echocardiographic recordings, 0.04 mg/kg of medetomidine was intramuscularly administered to each animal and LVOT velocity was calculated after 15 (T15), 50(T30) and 80(T80) minutes post drug administration. MeanSEM LVOT velocity values of cats in baseline was 1.060.04 m/s. There were significant differences between mean LVOT values between baseline and T15, T30 (p <0.001). Age and weight had no significant effect on LVOT velocity values (P>0.05). MeanSEM LVOT velocity of T15, T50 and T80 were 0.770.04 m/s, 0.800.02 m/s and 0.960.03 m/s. Our findings revealed significant decrease in mean LVOT velocity up to 50 minutes post medetomidine administration. The present study determined normal LVOT velocity range for a small population of cats before and after administration of intramuscular medetomidine.