Effect of medetomidine on left ventricular outflow tract (LVOT) velocity in cats; a doppler echocardiography study

Document Type : Short Communication

Authors

1 Department of Clinical Sciences. Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

2 Department of Small Animal Medicine & Radiology, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran

3 Department of Clinical Science, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.

4 Department of Epidemiology, Veterinary Medicine Faculty, University of Tehran, Tehran, Iran.

10.30466/vrf.2020.113899.2710

Abstract

The purpose of the present study is to evaluate effects of medetomidine on left ventricular outflow tract velocity in domestic short-haired cats. Eighteen healthy adult male domestic short-haired cats were used for this study. All animals were client owned. Echocardiography machine with 7.5 MHz tranducer was used. Specific veterinary Two-dimensional and pulse-waved echocardiogram images in apical five chamber right parasternal window were obtained and blood velocity in LVOT were calculated. After baseline echocardiographic recordings, 0.04 mg/kg of medetomidine was intramuscularly administered to each animal and LVOT velocity was calculated after 15 (T15), 50(T30) and 80(T80) minutes post drug administration. MeanSEM LVOT velocity values of cats in baseline was 1.060.04 m/s. There were significant differences between mean LVOT values between baseline and T15, T30 (p <0.001). Age and weight had no significant effect on LVOT velocity values (P>0.05). MeanSEM LVOT velocity of T15, T50 and T80 were 0.770.04 m/s, 0.800.02 m/s and 0.960.03 m/s. Our findings revealed significant decrease in mean LVOT velocity up to 50 minutes post medetomidine administration. The present study determined normal LVOT velocity range for a small population of cats before and after administration of intramuscular medetomidine.

Keywords



Articles in Press, Accepted Manuscript
Available Online from 15 June 2021
  • Receive Date: 06 September 2019
  • Revise Date: 22 November 2020
  • Accept Date: 28 November 2020