Iridociliary adenoma in a sheep (Shaal breed): A case report

Document Type : Clinical Report


1 DVM Graduated, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.

2 Department of Clinical Sciences, College of Veterinary Medicine, Karaj Branch, Islamic Azad University, Alborz, Iran.

3 Department of Clinical Sciences, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran;

4 Department of Pathobiology, Faculty of Veterinary Medicine, Lorestan University, Khorramabad, Iran.



Ocular tumors are rarely seen in farm animals. Iridociliary epithelial tumors are the second most common tumor of the eye in dogs and cats, but there is just one report of this tumor in sheep. This case report describes the history, clinical signs, histopathological and immunohistochemical findings, and surgical management of an iridociliary adenoma tumor in a 3-year-old Shaal sheep with signs of anorexia, depression, loss of vision, and a mass covering the left eye. The mass had protruded from the left eye globe but had not penetrated the periocular tissues. Enucleation was performed to excise the tumor. PAS and Alcian blue staining methods were done for the mass, but the result for both of them was negative. Slides were also immunostained for antibodies against cytokeratin AE1/AE3, Vimentin, and S-100 protein. The results were positive for vimentin but negative for cytokeratin and S-100. According to the results of histopathology and immunohistochemistry, the type of tumor was diagnosed as iridociliary adenoma. To our knowledge, it was the second report of the iridociliary tumor in the sheep and the first report of this tumor in the Shaal breed.


Articles in Press, Accepted Manuscript
Available Online from 14 June 2021
  • Receive Date: 05 September 2020
  • Revise Date: 06 January 2021
  • Accept Date: 07 January 2021