Document Type : Clinical Report
Authors
1 Animal Diseases Rapid Diagnosis Center, Southwest University, Chongqing, China
2 Chongqing Sanjiezhongxin Bioengineering Co. Ltd., Chongqing, China
3 Chongqing Health-Forever Biotech Co. Ltd., Chongqing, China
Abstract
Duck beak atrophy and dwarfism syndrome (BADS) is a newly emerged disease in China since 2015. In October 2017, an unidentified disease occurred in Cherry Valley ducks, Chongqing municipality, the southwest of China. The affected birds showed short beak and growth retardation clinical signs. The disease caused approximately 20.00% morbidity and serious weight loss due to retarded growth. In order to identify the causative agent of BADS, liver, spleen, lung and heart samples were collected for virus isolation, hemagglutination test, PCR identification, and partial gene sequencing. The isolated virus was tentatively named SC16. Hemagglutination test indicated that the virus was negative to chicken red blood cells. Based on the PCR and sequencing results, the causative agent of BADS was a novel duck-origin goose parvovirus (DGPV) while no another co-infection pathogen was found in this case. Further analysis could provide insights into the control strategies of DGPV in ducks.
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Main Subjects
- Chen H, Dou Y, Tang Y, et al. Isolation and genomic characterization of a duck-origin GPV-related parvovirus from Cherry Valley ducklings in China. PLoS One 2015; 10(10): 272-284.
- Chen H, Tang Y, Dou Y, et al. Evidence for vertical transmission of novel duck-origin goose parvovirus-related parvovirus. Transbound Emerg Dis 2016; 63(3): 243-247.
- Li PF, Zhang RH, Chen JH, et al. Development of a duplex semi-nested PCR assay for detection of classical goose parvovirus and novel goose parvovirus-related virus in sick or dead ducks with short beak and dwarfism syndrome. J Virol Methods 2017; 249: 165-169.
- Wang S, Cheng XX, Chen SL, et al. Identification of a novel goose parvovirus (GPV) recombinant associated with short beak and warfism syndrome in Mainland China, 2015. Infect Genet Evol 2016; 41: 289-291.
- Xiao S, Chen S, Cheng X, et al. The newly emerging duck-origin goose parvovirus in China exhibits a wide range of pathogenicity to main domesticated waterfowl. Vet Microbiol 2017; 203: 252-256.
- Johnston SL, Wellens K, Siegel C. Comparison of hemagglutination and hemadsorption tests for influenza detection. Diagn Microbiol Infect Dis 1992; 15(4): 363-365.
- Tamura K, Peterson D, Peterson N, et al. MEGA5: Molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol Biol Evol 2011; 28(10): 2731-2739.
- Lu YS, Lin DF, Lee YL et al. Infectious bill atrophy syndrome caused by parvovirus in a co-outbreak with duck viral hepatitis in ducks in Taiwan. Avian Dis 1993; 37(2): 591-596.
- Yu K, Ma X, Sheng Z, et al. Identification of goose-origin parvovirus as a cause of newly emerging beak atrophy and dwarfism syndrome in ducklings. J Clin Microbiol 2016; 54(8): 1999-2007.
- Li C, Li Q, Chen Z, et al. Novel duck parvovirus identified in Cherry Valley ducks (Anas platyrhynchos domesticus), China. Infect Genet Evol 2016; 44 : 278-280.
- Li P, Li J, Zhang R et al. Duck “beak atrophy and dwarfism syndrome” disease complex: Interplay of novel goose parvovirus-related virus and duck circovirus? Transbound Emerg Dis 2018; 65(2): 345-351.
- Ning K, Liang T, Wang MH, et al. Pathogenicity of a variant goose parvovirus, from short beak and dwarfism syndrome of Pekin ducks, in goose embryos and goslings. Avian Pathol 2018; 47(4): 391-399.
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