Veterinary Research Forum

Abstract Cutaneous squamous cell carcinoma (CSCC) is a clinically significant skin neoplasm in dogs, typically arising in areas exposed to chronic ultraviolet light. This report describes a 10-year-old intact male Pitbull dog weighing 33.00 kg that presented with a large, ulcerated, necrotic, and hemorrhagic mass in the inguinal mammary region. Initial hematological evaluation revealed marked leukocytosis with segmented neutrophilia, severe toxic changes, along with degenerated neutrophils observed in fine needle aspiration of the mass. Following a course of antibiotic therapy to control the severe infection, the mass was surgically excised using electrosurgery. The preoperative thoracic radiographs ruled out pulmonary metastasis. Histopathological examination confirmed the diagnosis of cutaneous SCC. Despite complete initial removal, tumor recurrence was noted seven months postoperatively. The owner declined further chemotherapy and surgical intervention. This report provides a comprehensive overview of the surgical, radiological, and histopathological findings of a massive cutaneous squamous cell carcinoma located in the ventral abdominal mammary region in a male Pitbull dog.

Abstract Hamartomas are mostly benign tumor-like malformations characterized by a disorganized overgrowth of mature cells and tissues indigenous to the affected anatomical site. A 20-day-old male Kurdish foal was presented to the Veterinary Teaching Hospital of Urmia University, Urmia, Iran, with a history of hematochezia and tenesmus. Clinical examination identified a pedunculated tissue mass within the rectal lumen. The abnormal mass was surgically excised via polypectomy under local anesthesia. Tissue samples were obtained, fixed in 10.00% neutral buffered formalin, and processed routinely for histopathological examination. Histopathological evaluation of the resected tissue confirmed the diagnosis of a cystic polypoid rectal hamartoma characterized by normal rectal epithelium overlying multiple cystic, blood-filled vascular spaces. The foal recovered without complications and no recurrence was noted during a long-term follow-up exceeding 18 months. This report underscored that congenital rectal hamartoma, while rare, should be considered as a differential diagnosis in neonatal foals presenting with hematochezia or dyschezia. Prompt surgical intervention is curative and associated with a favorable prognosis.