Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 17 2 2026 02 01 First report of acute reproductive disorder due to Mycoplasma suis in hyperprolific sows 135 139 732656 10.30466/vrf.2025.2048945.4595 EN Dung Thi Khanh Le Department of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Ho Chi Minh City, Vietnam Tram Ngoc Thi Ngo Department of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Ho Chi Minh City, Vietnam The Animal Biomedical Research Laboratories, Nong Lam University, Ho Chi Minh City, Vietnam Dung Thi Thuy Do Department of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Ho Chi Minh City, Vietnam Navetco National Veterinary Joint Stock Company, Ho Chi Minh City, Vietnam Nam Minh Nguyen Department of Biomedical Engineering Faculty of Medicine, University of Health Sciences Vietnam National University, Ho Chi Minh City, Vietnam Duy Tien Do Department of Infectious Diseases and Veterinary Public Health, Faculty of Animal Science and Veterinary Medicine, Nong Lam University, Ho Chi Minh City, Vietnam The Animal Biomedical Research Laboratories, Nong Lam University, Ho Chi Minh City, Vietnam 0000-0002-1825-2623 Journal Article 2025 01 05 Reproductive failure is the major problem in modern pig production, significantly affecting economic productivity. This study investigated factors associated with reproductive failure in the hyper prolific pig farms, focusing on abortion, mummification, stillbirth and sudden increased sow death. Seven individual sows with reproductive failure clinical signs were surveyed to evaluate the infection rate with related pathogens. Results showed the highest frequency of Mycoplasma suis infections with reproductive problems along with blood samples being 100% positive, fetal mummification rate of 33.33% and stillbirth rate of 25.00%. Additionally, 28.57% of the total blood samples exhibited porcine circovirus type 3 infection, while other pathogens were not detected. The percentage of concurrent infections with M. suis and porcine circovirus type 3 in reproductive sow was 28.57%. The partial 16S rRNA Porcine Haemoplasma is a trivial name for haemotropic Mycoplasma spp., which can attach to the surface of red blood cells leading to deformity and anaemia in a wide range of mammalian animals including pigs. Haemoplasma sequences in this study was absolutely clustered into Haemominutum group. This study demonstrated the first case of acute reproductive disorder due to M. suis reported in imported hyper prolific sows. https://vrf.iranjournals.ir/article_732656_76bb30110cab45e08d3b81d7bc2c2ee6.pdf