Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Rat adipose-derived mesenchymal stem cells aging reduction by zinc sulfate under extremely low frequency electromagnetic field exposure is associated with increased telomerase reverse transcriptase gene expression 89 96 25843 EN Ezzatollah Fathi Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran Raheleh Farahzadi Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Reza Rahbarghazi Stem Cell Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Hossein Samadi Kafil Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran Rahman Yolmeh Shefa Neurosciences Research Center, Khatam Al-Anbia Hospital, Tehran, Iran Journal Article 2017 06 14 Zinc as an essential trace element was reported to be involved in regulation of the growth and aging of cells. In this study, rat adipose-derived mesenchymal stem cells were exposed to extremely low frequency electromagnetic field (ELF-EMF) of 50 Hz and 20 mT to evaluate whether exposure to ELF-EMF in the presence of zinc sulfate (ZnSO4) affects the telomerase reverse transcriptase (TERT) gene expression and aging in mesenchymal stem cells (MSCs). The cell plates were divided into four groups including group I (control without ZnSO4 and ELF-EMF exposure); group II (ELF-EMF-exposure without ZnSO4); group III (ZnSO4 treatment without ELF-EMF exposure) and group ІV (ELF-EMF exposure with ZnSO4). In the presence of different concentrations of ZnSO4,cells viability, TERT gene expression and percentage of senescent cells were evaluated using colorimetric assay, real-time PCR and senescence-associated β-galactosidase activity assay, respectively. In this experiment, cells were exposed to ELF-EMF for 30 min per day for 21 days in the presence and absence of ZnSO4. The results revealed that ELF-EMF leads to a decrease in the expression of TERT gene and increase in the percentage of senescent cells. However, the ZnSO4 could significantly increase the TERT gene expression and decrease the aging of ELF-EMF-exposed MSCs. It seems that ZnSO4 may be a beneficial agent to delay aging of ELF-EMF-exposed MSCs due to the induction of TERT gene expression. Zinc as an essential trace element was reported to be involved in regulation of the growth and aging of cells. In this study, rat adipose-derived mesenchymal stem cells were exposed to extremely low frequency electromagnetic field (ELF-EMF) of 50 Hz and 20 mT to evaluate whether exposure to ELF-EMF in the presence of zinc sulfate (ZnSO4) affects the telomerase reverse transcriptase (TERT) gene expression and aging in mesenchymal stem cells (MSCs). The cell plates were divided into four groups including group I (control without ZnSO4 and ELF-EMF exposure); group II (ELF-EMF-exposure without ZnSO4); group III (ZnSO4 treatment without ELF-EMF exposure) and group ІV (ELF-EMF exposure with ZnSO4). In the presence of different concentrations of ZnSO4,cells viability, TERT gene expression and percentage of senescent cells were evaluated using colorimetric assay, real-time PCR and senescence-associated β-galactosidase activity assay, respectively. In this experiment, cells were exposed to ELF-EMF for 30 min per day for 21 days in the presence and absence of ZnSO4. The results revealed that ELF-EMF leads to a decrease in the expression of TERT gene and increase in the percentage of senescent cells. However, the ZnSO4 could significantly increase the TERT gene expression and decrease the aging of ELF-EMF-exposed MSCs. It seems that ZnSO4 may be a beneficial agent to delay aging of ELF-EMF-exposed MSCs due to the induction of TERT gene expression.

https://vrf.iranjournals.ir/article_25843_0e9a570f97a6f2a4e1326a10228176a4.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Ameliorative effects of Achillea millefolium inflorescences alcoholic extract on nicotine-induced reproductive toxicity in male rat: Apoptotic and biochemical evidences 97 104 25839 EN Ameneh Hasanzadeh Khosh Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Shapour Hasanzadeh Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Ali Shalizar Jalali Department of Basic Sciences, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran 0000-0002-9811-7754 Journal Article 2017 06 14 Nicotine (NIC) adversely influences male reproductive system. Achillea millefolium (Achm) as a medicinal plant is highly regarded for its antioxidant and anti-inflammatory properties. The present study was conducted to assess whether Achminflorescences alcoholic extract could serve as a protective agent against reproductive toxicity in NIC-exposed male rats. Adult male rats were randomly divided into six groups. Two groups received NIC at doses of 0.20 and 0.40 mg kg-1 per day in 0.50 mL sterile distilled water for 48 days intraperitoneally, respectively. The further two groups received NIC at doses of 0.20 and 0.40 mg kg-1 per day in 0.50 mL sterile distilled water for intraperitoneally along with Achm extract at a dose of 1.20 g kg-1 per day in 1 mL sterile distilled water orally for 48 days, respectively. A vehicle treated control group and an Achm-only treated group were also included. The NIC-exposed groups showed significant reductions in epididymal sperm count, motility, viability and serum levels of FSH, LH and testosterone as well as testicular antioxidant capacity. Moreover, the incidence of apoptosis and abnormality in spermatozoa along with testicular malondialdehyde and total nitrite levels were significantly higher in NIC-treated rats. The above-mentioned parameters were restored to near normal levels by Achm co-administration. These findings indicated thatAchmmay partially be protective against NIC-induced testicular toxicity.

https://vrf.iranjournals.ir/article_25839_5b0f06cd304f174c316b40e5b384a164.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 01 Detection and subtyping avian metapneumovirus from turkeys in Iran 105 108 25818 EN Mansour Mayahi Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran Hassan Momtaz Department of Veterinary Medicine, Veterinary Microbiology Section, Islamic Azad University of Shahrekord, Shahrekord, Iran Ramezan Ali Jafari Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran Pejman Zamani DVSc Student of Avian Health and Diseases, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran Journal Article 2017 06 14 Avian metapneumovirus (aMPV) causes diseases like rhinotracheitis in turkeys, swollen head syndrome in chickens and avian rhinotracheitis in other birds. Causing respiratory problems, aMPV adversely affects production and inflicts immense economic losses and mortalities, especially in turkey flocks. In recent years, several serological and molecular studies have been conducted on this virus, especially in poultry in Asia and Iran. The purpose of the present study was detecting and subtyping aMPV by reverse transcriptase polymerase chain reaction (RT-PCR) from non-vaccinated, commercial turkey flocks in Iran for the first time. Sixty three meat–type unvaccinated turkey flocks from several provinces of Iran were sampled in major turkey abattoirs. Samples were tested by RT-PCR for detecting and subtyping aMPV. The results showed that 26 samples from three flocks (4.10%) were positive for viral RNA and all of the viruses were found to be subtype B of aMPV. As a result, vaccination especially against subtype B of aMPV should be considered in turkey flocks in Iran to control aMPV infections.

https://vrf.iranjournals.ir/article_25818_876af3a1db90d050582dc4b1c2201198.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Association of Neospora caninum with reproductive performance in dairy cows: A prospective study from Iran 109 114 25820 EN Maryam Ansari-Lari Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran 0000-0002-8726-2040 Abbas Rowshan-Ghasrodashti Department of Internal Medicine, School of Veterinary Medicine, Islamic Azad University, Kazeroon Branch, Kazeroon, Iran Hadi Jesmani Department of Clinical Studies, School of Veterinary Medicine, Shiraz University, Shiraz, Iran Maliheh Masoudian Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran Mehrdad Badkoobeh Department of Food Hygiene and Public Health, School of Veterinary Medicine, Shiraz University, Shiraz, Iran Journal Article 2017 06 14 There is no prospective study from Iran to estimate the direct risk of Neospora caninum for pregnancy loss or reproductive factors. In addition, there is no report in the literature concerning the association of N. caninum with dystocia and sex of calves. Therefore, this study was conducted on a group of dairy cows in a large intensive production system during 2011 to 2013 in southern Iran to evaluate the impact of neosporosis on reproductive performance. A total of 253 cows which were diagnosed as pregnant during the first six months of the study were followed until calving or abortion. Reproductive data were collected and N. caninum serostatus was determined using ELISA. To investigate the association of abortion with N. caninum,survival analysis was performed using Cox proportional hazard model. The N. caninum seroprevalence in the study group was 30.40% (95% CI: 27.40, 36.10). The overall abortion rate was 12.25%, significantly higher in seropositive animals (20.80%) than seronegative ones (8.50%). Results of Cox model showed that serostatus of animal for N. caninum and season had significant associations with abortion (p < 0.01). Neospora caninum did not show significant association with other factors such as dystocia and sex of calves. In conclusion, neosporosis is responsible for 12.00% excess abortion risk in infected group and more than 30.00% of abortions could be preventable by control of Neospora in study population. Therefore, control of N. caninum would reduce the economic losses caused by parasite mainly due to pregnancy loss.

https://vrf.iranjournals.ir/article_25820_d5c9087190e4d541da83e0739edeb60c.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Does Achillea millefolium extracts possess prokinetic effects on the bovine abomasum thourgh M3 muscarinic receptors? 115 120 25835 EN Mojtaba Mohseni DVSc Candidate, Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Masoud Maham Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Bahram Dalir-Naghadeh Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Ghader Jalilzadeh-Amin Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran 0000-0003-2869-5492 Journal Article 2017 06 14 Displacement of the abomasum is a common disease of the gastrointestinal tract in dairy cattle. Abomasal displacement has been associated with abomasal hypomotility. Therefore, it is necessary to identify effective therapeutic agents that stimulate abomasal motility in cattle. Yarrow (Achillea millefolium) is traditionally used as a folk remedy for treatment of human gastrointestinal complaints in the northwest of Iran. This study investigated the effects of A. millefolium extracts on abomasal smooth muscle preparations from healthy cattle. The A. millefolium extracts (3 to3000 mg L-1) contracted the isolated of smooth muscle in a concentration-dependent manner, with an effective threshold concentration of 30 mg L-1 (p < 0.05). The strongest contraction by A. millefolium aqueous extracts in a concentration of 3000 mg L-1 was observed and amounted to 124.90 ± 10.80% of the control treatment. This action was unaffected by pretreatment with hexamethonium and indomethacin, but strongly reduced by verapamil, atropine and 4-DAMP. The inhibiting effect of 4-DAMP and atropine suggesting that the effect of A. millefolium extracts is mediated at least partly by M3 muscarinic acetylcholine receptor. The results suggested that A. millefolium has the potential prokinetic effect that may prevent or alleviate dysfunctions of gastrointestinal motility.

https://vrf.iranjournals.ir/article_25835_8200e2e850224e4cea691cdc3ad0da2d.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 A high prevalence of tylosin resistance among Staphylococcus aureus strains isolated from bovine mastitis 121 125 25844 EN Farhad Bahraminia Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Seyed Reza Emadi Department of Theriogenology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran Mohammad Emaneini Department of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran Nima Farzaneh Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Mehrnaz Rad Department of Pathobiology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Babak Khoramian Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran 0000-0002-4962-2797 Journal Article 2017 06 14 The macrolides appear to have considerable effects for treatment of bovine mastitis because of excellent diffusion into the mammary gland, long half-life, low protein binding, high intracellular concentration and lipid solubility. Acquired resistance to macrolides in Staphylococcus aureus is primarily related to target-site modification through acquisition of an erm gene. In the present study the prevalence of both phenotypic and genotypic tylosin resistance in S. aureus isolates (n = 103) from subclinical mastitis in nine dairy farms belonging to three different province of Iran were investigated. Overall, ermA, ermB and ermC was found in 7.80%, 32.00%, and 20.40% of S.aureus isolates, respectively. A very high percent of isolates (56.90%) were resistant to tylosin. MIC90 and MIC50 values were 64 and 32 µg mL-1, respectively. Most of tylosin resistant isolates did not harbour any erm gene but ermB was dominant gene among 58 tylosin resistant isolates of S. aureus. In overall, tylosin resistance was prevalent in S. aureus isolates obtained from bovine mastitis in Iran.

https://vrf.iranjournals.ir/article_25844_b4eafd1174bee5bc3e87d06b7748cc2a.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 01 Effects of dietary supplementation of waste date’s vinegar on performance and improvement of digestive tract in broiler chicks 127 132 25819 EN Shima Tasharofi Department of Animal Science Researches, Agriculture and Natural Resources Education and Research Center of Kerman, Kerman, Iran Laleh Yazdanpanah Goharrizi Department of Animal Science Researches, Agriculture and Natural Resources Education and Research Center of Kerman, Kerman, Iran Farhad Mohammadi Graduate Student, Department of Animal Science, Faculty of Agriculture, Shahid Bahonar University of Kerman, Kerman, Iran Journal Article 2017 06 14 Two hundred 1-day-old commercial broilers (Ross 308) were used to determine the effects of diets supplementation with waste date’s vinegar (WDV) on the growth and performance of digestive tract over a 42-days growing period. Chicks were randomly allocated to one of five experimental diets supplementing as 0 (control), 1, 2, and 3% of WDV and 2% industrial vinegar (IV). Broilers and their feed consumptions were weighed at the trial beginning and days 10, 21, 35 and 42 of experimental period. Moreover, one chick from every replicate was killed at days 21 and 42 to measure development of digestive tissues and morphology and microbiology of small intestine. Although the final body weight was higher following IV and 1% WDV usage, feed conversion ratio was negatively affected by IV usage compared to control (p < 0.05). Relative weight of different parts of small intestine was not affected by experimental diets. Villus height and width were reduced linearly in WDV, IV and control groups (p < 0.05), but crypt depth was not different among experimental diets. Also, ileum microbiota was not affected by treatments. Results indicated that diet supplementation with WDV has positive effects on growth performance and histomorphology of jejunum in broilers.

https://vrf.iranjournals.ir/article_25819_5361ef0c3c103c396bb6c7a24e638b5e.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Evaluation of glutathion peroxidase activity, trace minerals and weight gain following administration of selenium compounds in lambs 133 137 26478 EN Pedram Yaghmaei DVSc Candidate, Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Aligholi Ramin Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Siamak Asri-Rezaei Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran 0000-0002-3981-3290 Asghar Zamani Department of Nano Chemistry, Faculty of Science, Urmia University, Urmia, Iran Journal Article 2017 07 20 Blood selenium and trace minerals play an important role in animal’s health and production. The aims of this study were to determine selenium effect on blood glutathione peroxidase (GPX) activity, trace minerals and weight gain in lambs. Twelve female Makuei breed were studied for 63 days in groups of control, nanoselenium (NanoSe) and sodium selenite (NaSe). Mean concentrations of GPX, Cu and Fe in selenium supplemented groups were higher than in control group but the differences were not significant. Mean GPX and selenium was significant among the bleeding times, for Cu and Zn significant occasionally while not for weight gain. The percentages of weight gain in groups were 34.20, 38.90 and 36.30, respectively, which was not different. The individual comparison of parameters among groups showed differences for GPX, selenium and Cu. Correlations were observed between weight & Fe, weight & GPX, weight & selenium, Zn & Fe and GPX & selenium in NanoSe group. Weight gain showed negative correlations with Fe and positive correlation with GPX. In conclusion, selenium compounds increased GPX activity and selenium in which it was predominant in NanoSe than in NaSe group. Selenium compounds showed no effects on Cu, Zn and Fe but caused weight gain to increase. NanoSe revealed correlations between weight gain, GPX, Fe and selenium and was preferable to NaSe. Thus, the effect of NanoSe on reducing the oxidative stress and increased weight gain was acceptable and probably an option to NaSe administration in lambs.

https://vrf.iranjournals.ir/article_26478_ebb9a55061af33b68d38f7ce72e4460f.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 01 Molecular detection, infection rate and vectors of Theileria lestoquardi in goats from West Azerbaijan province, Iran 139 144 25836 EN Seyyed Mostafa Mohammadi Graduate Student, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Bijan Esmaeilnejad Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Ghader Jalilzadeh-Amin Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran 0000-0003-2869-5492 Journal Article 2017 06 14 This study was aimed to determine the infection rate and vectors of Theileria lestoquardi in goats from West Azerbaijan province, Iran. A total of 400 blood samples were collected from 40 randomly selected flocks in the study area from June to September, 2014. Out of 400 blood samples examined using microscopic examination, a number of 14 goats (3.50%) were positive for Theileria spp., whereas 25 goats (6.25%) yielded a specific T. lestoquardi SSU-rRNA fragment (235 bp). The prevalence of theileriosis in goats estimated by semi-nested PCR was significantly higher than the prevalence estimated by microscopic examination of the blood smears. The prevalence of Theileria infection in different age and sex groups of goats was not significantly different. The highest and lowest prevalence of Theileria infection was in July (12.00%) and September (2.00%), respectively. A number of 315 adult Ixodid ticks were also collected from naturally infested goats and they were characterized. Out of 315 examined ticks, a number of 37 ticks including Hyalomma marginatum (65.20%), Rhipicephalus turanicus (44.00%), and Dermacentor marginatus (68.70%) were infected by T. lestoquardi. Based on the obtained results, it was concluded that the semi-nested PCR assay based on SSU-rRNA gene is a valuable method for epidemiological investigation of caprine theileriosis. The results showed that H. marginatum, R. turanicus and D. marginatus can be considered as risk factor in the epidemiology of T. lestoquardi.

https://vrf.iranjournals.ir/article_25836_94f2bea7eb6186bb607e796153b2c343.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 01 Therapeutic effects of marshmallow (Althaea officinalis L.) extract on plasma biochemical parameters of common carp infected with Aeromonas hydrophila 145 153 25822 EN Mahdi Banaee Department of Aquaculture, Faculty of Environment and Natural Resources, Behbahan Khatam Al-Anbia University of Technology, Behbahan, Iran Vahid Soleimany Department of Aquaculture, Faculty of Environment and Natural Resources, Behbahan Khatam Al-Anbia University of Technology, Behbahan, Iran Behzad Nematdoost Haghi Department of Aquaculture, Faculty of Environment and Natural Resources, Behbahan Khatam Al-Anbia University of Technology, Behbahan, Iran Journal Article 2017 06 14 This study evaluated preclinical and clinical safety of marshmallow (Althaea officinalis L.) extract as a naturopathic medicine in common carp deliberately infected with Aeromonas hydrophila. The fish were fed 0 (control), 2.50, 5.00 and 10.00 g of marshmallow extract for 60 days in a preclinical experiment and then, challenged with A. hydrophila for a 10-day experiment. Significant increases were observed in aspartate aminotransferase (AST), lactate dehydrogenase (LDH), alkaline phosphatase (ALP), creatine phosphokinase (CPK) activities and plasma creatinine levels in fish fed 10 g marshmallow extract per kg feed. However, alanine aminotransferase (ALT) significantly decreased on day 60. The fish fed 2.50 g marshmallow extract per kg feed indicated increased levels of total protein and globulin. There were no significant changes in albumin levels (p > 0.05). 2.50 and 5.00 g marshmallow significantly decreased triglyceride and cholesterol levels and increased glucose levels (p < 0.05). A. hydrophila significantly increased AST, ALT, LDH, ALP and CPK activities and plasma glucose, cholesterol, triglycerides and creatinine levels after 10 days (p < 0.05). Total plasma protein, albumin and globulin levels in fish challenged with A. hydrophila were significantly lower than the control group (p < 0.05). Marshmallow extract at 5.00 and 10.00 g can adjust plasma biochemical parameters in fish challenged with A. hydrophila. The results of preclinical studies and pharmaceutical toxicity of marshmallow extract revealed that dietary levels lower than 5.00 g were safe and effective. The results of this clinical study demonstrated that marshmallow extract (5.00 g kg-1 feed) can protect fish against A. hydrophila.

https://vrf.iranjournals.ir/article_25822_a1b865daa05b1b1283171c4d28c02ec6.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Curcumin-loaded poly lactic-co-glycolic acid nanoparticles effects on mono-iodoacetate -induced osteoarthritis in rats 155 161 25825 EN Firoozeh Niazvand Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Layasadat Khorsandi Student Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Cell and Molecular Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Mohammadreza Abbaspour Targeted Drug Delivery Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran Mahmoud Orazizadeh Cell and Molecular Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Negar Varaa Cell and Molecular Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Mahtab Maghzi Cell and Molecular Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Kheironesa Ahmadi Cell and Molecular Research Center, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran Journal Article 2017 06 14 Curcumin has been found to be very efficacious against many different types of diseases. However, the major disadvantage associated with the use of curcumin is its low systemic bioavailability. In the present study the protective effects of curcumin-loaded poly lactic-co-glycolic acid nanoparticles (nanocurcumin) against mono-iodoacetate-induced osteoarthritis in rats was investigated. Mono-iodoacetate was injected into right knee joints to induce osteoarthritis. In experimental groups, 14 days after injection of mono-iodoacetate, curcumin (200 mg kg-1) and nanocurcumin (200 mg kg-1) were gavaged, respectively, for two weeks. Then the rats were sacrificed and the right knee joints were removed and fixated in 10% formalin for histological assessments. Cellularity and matrix staining were significantly increased in articular cartilage of curcumin-treated animals compared to mono-iodoacetate group (p < 0.01). These effects were significantly (p < 0.01) more in nanocurcumin-treated animals. These results suggested that administration of nanocurcumin prevented the structural changes of articular cartilage in mono-iodoacetate modelofosteoarthritis in rats.

https://vrf.iranjournals.ir/article_25825_de447028949b3471aa2617ad9db5a97f.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Effect of dietary turmeric and cinnamon powders on meat quality and lipid peroxidation of broiler chicken under heat stress condition 163 169 25821 EN Payam Baghban Kanani Department of Animal Sciences, Faculty of Agriculture, Urmia University, Urmia, Iran Mohsen Daneshyar Department of Animal Sciences, Faculty of Agriculture, Urmia University, Urmia, Iran 0000-0003-1854-210X Javad Aliakbarlu Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran 0000-0003-0858-682x Fatemeh Hamian Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran Journal Article 2017 06 14 Two hundred and fifty male 1-day-old broiler chicks (Ross 308) were used to investigate the effects of dietary supplementation of turmeric and cinnamon powders on meat quality and lipid peroxidation of broilers under heat stress condition. The five treatment groups were control (recommended temperature for Ross 308), heat stressed (32 ± 1 ˚C from 9:00 AM to 5:00 PM during finisher period) and heat stressed birds fed with 0.50% turmeric, 0.50% cinnamon and a blend of cinnamon and turmeric (0.25% turmeric + 0.25% cinnamon). The results showed that there were no significant differences between the treatments for ether extract, ash and crude protein contents of thigh meat at 42 day of age (p > 0.05). Heat stress decreased the pH value and dry matter (DM) content of thigh meat, whereas the consumption of all experimental diets (turmeric, cinnamon and both of them) compensated the decreased pH and DM values due to heat stress to some extent but could not restore them to the level of control treatment (p< 0.01). Furthermore, the thigh meat lightness was increased under heat stress (p < 0.05). The thiobarbituric acid reactive substances and free radicals scavenging activity were increased in thigh meat of broilers reared under heat stress (p < 0.05), while these parameters were reduced by the combination of both plants (p < 0.01). It was concluded that heat stress reduces antioxidant properties and quality of thigh meat and dietary supplementation of turmeric and cinnamon powders together can remove the detrimental effects of heat stress on meat quality.

https://vrf.iranjournals.ir/article_25821_9c75e36585c849bbac315c81661b0821.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 01 Management of a bilateral mandibular fracture in a single-humped camel 171 174 25823 EN Hadi Imani Rastabi Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran Abdolvahed Moarabi Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran 0000-0002-0216-6325 Ahmad Khajeh Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran Narges Kavosi Department of Clinical Science, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran Journal Article 2017 06 14 In the present case report, the comprehensive management of a bilateral mandibular fracture in a single-humped camel including pre-, peri- and post-operative cares is described. A one-year-old camel with the overhanging of the rostral part of the lower jaw which occurred seven days ago was presented. After clinical and radiographic examinations, a bilateral mandibular fracture at the caudal part of canine teeth was diagnosed. It was decided to repair the fracture surgically under general anesthesia. The camel was restrained in sitting position and was remained in this position during anesthesia and surgery period. After premedication with acepromazine (0.10 mg kg-1) and xylazine (0.20 mg kg-1) intramuscularly, anesthesia was induced using ketamine and diazepam intravenously (2.00 and 0.10 mg kg-1, respectively). Maintenance of anesthesia was performed by repeated doses of xylazine and ketamine intravenously (0.10 and 1.00 mg kg-1, respectively) as needed. After preparation of the oral cavity, the fracture was reduced and an interfragmentary wire and an interdental wire (1.00 mm diameter size) were applied on each side of the mandible for the fixation of fracture segments. After two months, the interdental wires were removed while the interfragmentary wires were left intact. Follow up the camel three months after surgery, showed the full ability of prehension and chewing of roughages by the camel.

https://vrf.iranjournals.ir/article_25823_c49b360013e94c4d5e72d5e7cc3742ed.pdf

Faculty of Veterinary Medicine, Urmia University Veterinary Research Forum 2008-8140 8 2 2017 06 15 Bilateral simple ectopic kidney in a cat 175 177 25824 EN Masoud Rajabioun Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Hamideh Salari Sedigh Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Ali Mirshahi Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran Journal Article 2017 06 14 Bilateral simple ectopic kidney was diagnosed in an apparently healthy 3-year-old, female domestic short hair cat, incidentally based on radiology and ultrasonography examination. The cat was presented for routine examination without any complaint. In clinical evaluation, no significant abnormal clinical sign was seen except for the absence of both kidneys in their proper location in abdominal palpation, which they were palpated more caudally. Radiography revealed silhouettes of soft tissue opacity in the caudal part of the abdominal cavity superimposed on urinary bladder. Ultrasonography confirmed the presence of both kidneys more caudally. The left kidney was dorsal to the urinary bladder and the right kidney located cranially than the left one. Each kidney showed normal shape and size and imaged in their proper side. Hematological, biochemical and urinalysis examinations showed normal values. Ectopic kidney can be diagnosed in feline patients as an incidental finding but it is important to evaluate the kidney for concurrent problems.

https://vrf.iranjournals.ir/article_25824_768d084123cb2ed6e871ad2019d3ae8a.pdf