Pathology
Moosa Javdani; Mohammad Hashemnia; Zahra Nikousefat; Mohammad Ghasemi
Volume 8, Issue 3 , September 2017, , Pages 265-268
Abstract
Osteoma is an uncommon bone tumor in avian species and other animals. A 2-year-old male canary (Serinus canaria) with a history of an oval mass in the left wing for several months was examined. Radiographs showed a radio-opaque mass. Upon the bird’s owner request, the canary was euthanatized and ...
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Osteoma is an uncommon bone tumor in avian species and other animals. A 2-year-old male canary (Serinus canaria) with a history of an oval mass in the left wing for several months was examined. Radiographs showed a radio-opaque mass. Upon the bird’s owner request, the canary was euthanatized and submitted for necropsy. The histopathologic examination revealed numerous trabeculae consisting of both woven and lamellar bone covered by one to several rows of normal osteoblasts. The trabeculae were closely packed, having only small intertrabecular spaces which contained proliferating osteoblasts, sinusoids and myeloid tissue. Based on clinical, radiographic, and histopathologic findings, the mass was diagnosed as extraskeletal osteoma. To the best of authors’ knowledge, extraskeletal osteoma has not been reported in in avian species so far, and this is the first report of osteoma tumor in the birds. However, benign tumors of bones are extremely rare in the birds, osteoma should be considered as a differential diagnosis in the birds with bone lesions.
Small Animal Surgery
Zahra Nikousefat; Mohammad Hashemnia; Moosa Javdani
Volume 7, Issue 1 , March 2016, , Pages 79-83
Abstract
In the present study, we described cyto-histopathological features and immunophenotyping of the large B-cell lymphoma in an 8-year-old mixed breed dog with applying the World Health Organization (WHO) system of classification of canine lymphomas. In fine-needle aspiration (FNA), lymph nodes were involved ...
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In the present study, we described cyto-histopathological features and immunophenotyping of the large B-cell lymphoma in an 8-year-old mixed breed dog with applying the World Health Organization (WHO) system of classification of canine lymphomas. In fine-needle aspiration (FNA), lymph nodes were involved by neoplastic cells of intermediate to large size with deep blue cytoplasm; consist of centroblasts, immunoblast and medium-sized cells. Histopathologically, the follicles and sinuses of lymph nodes were replaced by sheets of numerous immunoblasts (less than 90.0% of total cells) and centroblasts. Numerous mitotic figures were also observed. Immunohistochemical analysis presented that the neoplastic cells express B-cell phenotype CD20 and CD79a, but do not stain for T phenotype CD3. On the basis of cytology, histopathology and immunohistochemical findings, the present tumor was diagnosed as diffuse large B-cell lymphoma, high-grade centroblastic type (DLBCL-CB) according to WHO histological classification. Applying this classification system for diagnosis of canine lymphomas is very useful and has a high accuracy and consistency. However, further co-operative studies between clinicians and pathologists should be performed, in order to improve the effectiveness of this classification.
