Document Type: Original Article
Department of Basic Sciences, Faculty of Veterinary Medicine, Garmsar Branch, Islamic Azad University, Garmsar, Iran
Department of Basic Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran
Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahrekord University, Shahrekord, Iran
Department of Agricultural Technology, Faculty of Technology, Mahasarakham University, Mahasarakham, Thailand
Department of Physiology, Faculty of Advanced Sciences and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
The effect of Shirazi thyme as a medicinal plant on oxidant status (lipid peroxidation, protein oxidation, total antioxidant capacity and catalase activity) and absorptive surface area were measured in three segments of small intestine in cold-induced pulmonary hypertensive chickens. Birds were reared at 4 groups (thyme 0, 0.25, 0.5 and 1 % of diet) for 42 days. To induce pulmonary hypertension, the temperature was gradually decreased. The body weight was increased in thyme-0.25% birds in compared to control ones while it was decreased in thyme-1% birds. The feed consumption was only increased in thyme-1% birds. The feed conversion ratio was lower in thyme-0.25% birds and higher in thyme-1% birds than control ones. The duodenal and jejunal villus surface area was lower in thyme-1% birds than control ones while it was greater in the thyme-0.5% birds. The ileal villus surface area and duodenal laminae properia thickness was also greater in thyme-0.5% birds. Lipid peroxidation was only decreased in the duodenum and ileum of thyme-0.5% birds compared to control ones, whereas it was increased in the duodenum and jejunum of thyme-1% birds. Catalase activity was only elevated in the duodenum and jejunum of thyme-1% fed chickens. Total antioxidant capacity was increased in the duodenum, jejunum and ileum of thyme-0.5% birds. It is concluded that Shirazi thyme has beneficial effects on growth performance, intestinal absorptive surface area / secretory system and pulmonary hypertension response at low doses (0.25 and 0.5% fed) whereas high dose of this plant may be toxic (1% fed).