Seroepidemiological feature of Chlamydia abortus in sheep and goat ‎population located in northeastern Iran

Document Type : Short Communication

Authors

1 Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran

2 Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran

3 Veterinary Administration of Khorasan Razavi province, Mashhad, Iran

Abstract

Chlamydia abortus (C. abortus) is a Gram-negative intracellular bacteria responsible for major economic losses due mainly to infection and subsequent induction of abortion in several animal species and poses considerable public health problems in humans. This study was conducted to determine the prevalence of antibody against C. abortus in sheep and goat population of Khorasan Razavi province located in northeastern Iran. Four hundred fifty-two (271 sheep and 181 goats) sera samples from 40 sheep/goat epidemiologic units located in 11 counties were selected. Sera were assayed for antibodies against C. abortus using ELISA assay. Out of 452 sheep and goat sera, 44 [9.70% (95.00%CI: 7.10%-12.40%)] were positive for C. abortus antibodies. 28 out of 40 epidemiologic units (70.00%) and 10 out of 11 counties (91.00%), at least one seropositive sample was found. There was no significant difference between the seropositivity of sheep and goats. Age, sex, and location did not show significant relationship with the test results. The results showed that C. abortus was circulating in wide parts of Khorasan Razavi province. Considering the economic and public health importance of C. abortus, measures should be taken to help prevent its spread and to reduce the zoonotic risk of C. abortus in the studied region.

Keywords


Ganta RR. Chlamydiaceae. In: McVey DS, Kennedy M, Chengappa MM (Eds). Veterinary microbiology. Oxford, UK: Wiley-Blackwell 2013; 279-282.
World organization for animal health website. Enzootic abortion of ewes (Ovine chlamydiosis). Available at: http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.07.06_ENZ_ABOR.pdf. Accessed August 20, 2018.
Heidari S, Derakhshandeh A, Firouzi R, et al. Molecular detection of Chlamydophila abortus, Coxiella burnetii, and Mycoplasma agalactiae in small ruminants’ aborted fetuses in southern Iran. Trop Anim Health Prod 2018; 50(4):779-785.
Kalender H, Kilic A, Eroksuz H, et al. Identification of Chlamydophila abortus infection in aborting ewes and goats in Eastern Turkey. Rev Med Vet (Toulouse) 2013; 164(6):295-301.
Szeredi L, Jánosi Sz, Tenk M, et al. Epidemiological and pathological study on the causes of abortion in sheep and goats in Hungary (1998-2005). Acta Vet Hung 2006; 54(4):503-515.
Aitken ID, Longbottom D. Chlamydial abortion. In: Aitken ID, (Ed.). Diseases of sheep. 4th ed. Oxford, UK: Blackwell Inc. 2008; 105-111.
Scott PR. Sheep Medicine. London, UK: Manson publishing Ltd. 2010; 60-62.
Kerr K, Entrican G, McKeever D, et al. Immuno-pathology of Chlamydophila abortus infection in sheep and mice. Res Vet Sci 2005; 78(1):1-7.
Pospischil A, Thoma R, Hilbe M, et al. Abortion in woman caused by caprine Chlamydophila abortus (Chlamydia psittacci serovar 1). Swiss Med Wkly 2002; 132(5-6):64-66.
Meijer A, Brandenburg A, de Vries J, et al. Chlamydophila abortus infection in a pregnant woman associated with indirect contact with infected goats.. Eur J Clin Microbiol 2004; 23(6):487-490.
Rodolakis A, Mohamad KY. Zoonotic potential of Chlamydophila. Vet Microbiol 2010; 140(3-4):382-391.
Esmaeili H, Bolourchi M, Mokhber-Dezfouli MR. Seroprevalence of Chlamydia abortus infection in sheep and goats in Iran. Iran J Vet Med 2015; 9(2):73-77.
Thrusfield M, Christley R. Veterinary Epidemiology. 4th ed. Chichester, UK: John Wiley & Sons 2018; 70-71.
Alem M, Asadpour R, Jafari Joozani R, et al. Molecular detection of Chlamydophila abortus in aborted fetal tissues by using polymerase chain reaction (PCR) in Tabriz, northwest of Iran. J Cell Mol Res 2017; 9(1): 35-38.
Masala G, Porcu R, Sanna G, et al. Role of Chlamydophila abortus in ovine and caprine abortion in Sardinia, Italy. Vet Res Commun 2005; 29 (Suppl 1):117-123.
Cislakova L, Halanova M, Kovacova D, et al. Occurrence of antibodies against Chlamydophila abortus in sheep and goats in the Slovak Republic. Ann Agric Environ Med 2007; 14(2):243-245.
Pinheiro Junior JW, Mota RA, Piatti RM, et al. Seroprevalence of antibodies to Chlamydophila abortus in ovine in the State of Alagoas, Brazil. Braz J Microbiol 2010; 41(2):358-364.
Al-Qudah KM, Sharif LA, Raouf RY, et al. Sero-prevalence of antibodies to Chlamydophila abortus shown in Awassi sheep and local goats in Jordan. Vet Med Czech 2004; 49(12):460-466.
McCauley LM, Lancaster MJ, Butler KL, et al. Serological analysis of Chlamydophila abortus in Australian sheep and implications for the rejection of breeder sheep for export. Aust Vet J 2010; 88(1-2):32-38.
Cubero-Pablo MJ, Plaza M, Pérez L, et al. Sero-epidemiology of chlamydial infections of wild ruminants in Spain. J Wildl Dis 2000; 36(1):35-47.