Veterinary Research Forum
Vet Res Forum

Epidermal growth factor concentration in milk of healthy water buffaloes (Bubalus bubalis)

Document Type : Short Communication

Authors

Filiz Kazak 1
Gul Fatma Yarim 2
Ayris Gokceoglu 2
Mehmet Kemal Delmecioglu 2
Murat Yarim 3

1 Department of Biochemisty, Faculty of Veterinary Medicine, Hatay Mustafa Kemal University, Hatay, Turkiye

2 Department of Biochemistry, Faculty of Veterinary Medicine, Ondokuz Mayis University, Samsun, Turkiye

3 Department of Pathology, Faculty of Veterinary Medicine, Ondokuz Mayis University, Samsun, Turkiye

https://doi.org/10.30466/vrf.2021.528757.3167
Abstract
Epidermal growth factor (EGF) has biological roles, including embryonic organ development, breast morphogenesis, breast cell proliferation, and mammary development. This study aimed to measure EGF concentration and evaluate its relationship with somatic cell count (SCC) in healthy water buffaloes (Bubalus bubalis) milk. The study material was constituted of 120 milk samples obtained from 30 healthy water buffaloes between the ages of 3 - 6 years, negative for California mastitis test and SCC less than 3.00 × 105 cells mL-1 milk. In milk serum samples, the EGF concentration was measured using a bovine-specific enzyme-linked immunosorbent assay kit. Epidermal growth factor concentration in the buffalo milk was ranged from 4.30 to 9.80 ng mL-1, with a mean of 8.30 ± 1.50 ng mL-1. Positive correlation between milk SCC values and EGF concentrations was recorded in water buffaloes. Further research is required to evaluate the content of milk EGF in different species of animals because of the EGF effective role in mammary gland and intestinal mucosa.

Keywords

Epidermal growth factor
Milk
Somatic cell counting
Water buffalo
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Veterinary Research Forum
Volume 13, Issue 4
Autumn 2022
Pages 593-596

  • Receive Date 21 April 2021
  • Revise Date 28 July 2021
  • Accept Date 31 July 2021

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