Volume 15 (2024)
Volume 14 (2023)
Volume 13 (2022)
Volume 12 (2021)
Volume 11 (2020)
Volume 10 (2019)
Volume 9 (2018)
Volume 8 (2017)
Volume 7 (2016)
Volume 6 (2015)
Volume 5 (2014)
Volume 4 (2013)
Volume 3 (2012)
Volume 2 (2011)
Volume 1 (2010)
Effect of thymoquinone on acetic acid-induced visceral nociception in rats: role of central cannabinoid and α2-adrenergic receptors

Somayyeh Naderi; Esmaeal Tamaddonfard; Saeid Nafisi; Farhad Soltanalinejad-Taghiabad

Volume 15, Issue 3 , March 2024, , Pages 131-138

  Thymoquinone (TQ) is the main biologically active substance of Nigella sativa (black seeds). It has anti-cancer, anti-inflammatory, anti-diabetic, anti-oxidative and anti-nociceptive properties. This study was aimed to explore the effect of TQ on acetic acid-induced visceral nociception. The central ...  Read More

Cerebellar fastigial nucleus histamine and its H2 but not H1 receptors might inhibit acetic acid-induced visceral nociception and improve motor coordination in rats: role of opioid system

Fereshteh Anbarian; Esmaeal Tamaddonfard; Amir Erfanparast; Farhad Soltanalinejad-Taghiabad

Volume 14, Issue 10 , October 2023, , Pages 549-557

  The cerebellum and its deep nuclei contribute to the regulation of important functions including motor coordination and pain. Histamine modulates some functions of the fastigial nucleus (FN) such as motor coordination. In this study, by application of histamine and activation of its H1 and H2 receptors, ...  Read More

Ventrolateral periaqueductal gray exogenous and endogenous histamine attenuates sciatic nerve chronic constriction injury-induced neuropathic pain through opioid receptors

Sara Salimi; Esmaeal Tamaddonfard; Farhad Soltanalinejad-Taghiabad

Volume 12, Issue 4 , December 2021, , Pages 429-436

  The aim of the present study was to investigate the effects of intra-ventrolateral periaqueductal gray (vlPAG) microinjection of histamine and thioperamide (a histamine H3 receptor antagonist/inverse agonist) on neuropathic pain. To explore the possible mechanism, naloxone was microinjected alone or ...  Read More

Effects of intraperitoneal and intracerebroventricular injection of cinnamaldehyde and yohimbine on blood glucose and serum insulin concentrations in ketamine-xylazine induced acute hyperglycemia

Farshad Safaei; Esmaeal Tamaddonfard; Saeed Nafisi; Mehdi Imani

Volume 12, Issue 2 , June 2021, , Pages 149-156

  This study was designed to investigate the effects of peripheral [intraperitoneal (IP)] and central [intracerebroventricular (ICV)] administration of cinnamaldehyde on concentrations of blood glucose and serum insulin in the acute hyperglycemia induced by ketamine/xylazine. Yohimbine (a α2-adrenoceptor ...  Read More

Effects of histidine and vitamin C on isoproterenol-induced acute myocardial infarction in rats

Masoumeh Moradi-Arzeloo; Amir Abbas Farshid; Esmaeal Tamaddonfard; Siamak Asri-Rezaei

Volume 7, Issue 1 , March 2016, , Pages 47-54

  In the present study, we investigated the effects of histidine and vitamin C (alone or in combination) treatments against isoproterenol (a β-adrenergic receptor agonist)-induced acute myocardial infarction in rats. We used propranolol (a β-adrenergic receptor blocker) to compare the results. ...  Read More

Role of opioid system in verapamil-induced antinociception in a rat model of orofacial pain

Esmaeal Tamaddonfard; Amir Erfanparast; Mina Taati; Milad Dabbaghi

Volume 5, Issue 1 , March 2014, , Pages 49-54

  Calcium, through its various channels involves in local, spinal and supra-spinal transmission of pain. In the present study, we investigated the separate and combined treatment effects of verapamil (a calcium channel blocker), morphine (an opioid agonist) and naloxone (an opioid antagonist) on pain in ...  Read More