Volume 15 (2024)
Volume 14 (2023)
Volume 13 (2022)
Volume 12 (2021)
Volume 11 (2020)
Volume 10 (2019)
Volume 9 (2018)
Volume 8 (2017)
Volume 7 (2016)
Volume 6 (2015)
Volume 5 (2014)
Volume 4 (2013)
Volume 3 (2012)
Volume 2 (2011)
Volume 1 (2010)
Development of polyclonal heavy chain antibodies targeting programmed death ligand-1

Akbar Oghalaie; Alireza Shoari; Fatemeh Kazemi-Lomedasht; Fatemeh Rahimi-Jamnani; Fereidoun Mahboudi; Hajarossadat Ghaderi; Mohammad Hosseininejad-Chafi; Reza Moaazami; Arghavan Ashja Ardalan; Somayeh Piri-Gavgani; Delavar Shabazzadeh; Mahdi Behdani

Volume 14, Issue 6 , June 2023, , Pages 323-328

  Programmed death ligand-1 (PD-L1, CD274 and B7-H1) has been described as a ligand for immune inhibitory receptor programmed death protein 1 (PD-1). With binding to PD-1 on activated T cells, PD-L1 can prevent T cell responses via motivating apoptosis. Consequently, it causes cancers immune evasion and ...  Read More

Indigenous production, characterization and evaluation of polyclonal antibody against Camelus dromedarius immunoglobulin

Azadeh Yektaseresht; Zahra Hemati; Amir Arsalan Khorsand; Shoor Virsingh

Volume 13, Issue 4 , December 2022, , Pages 603-606

  No diagnostic kits and reagents are available in the market to detect and evaluate camel immune responses to different pathogens. This study aimed to produce sheep anti-camel (Camelus dromedarius) polyclonal antibodies (pAbs) and to determine the specificity with other species immunoglobulin. Immunoglobulins ...  Read More

Development and characterization of polyclonal antibody against human kappa light chain in rabbit

Mojgan Esparvarinha; Hamid Nickho; Leili Aghebati; Jalal Abdolalizadeh; Hadi Nasiri; Zahra Valedkarimi; Jafar Majidi

Volume 10, Issue 3 , September 2019, , Pages 207-211

  Polyclonal antibodies against kappa light chain are used to diagnose diseases producing free light chain. The kappa and lambda light chains are products of immunoglobulin synthesis and released into the circulation in minor amounts such as serum, cerebrospinal fluid, urine and synovial fluid in normal ...  Read More

Production and purification of polyclonal antibody against F(ab')2 fragment of human immunoglobulin G

Hadi Nasiri; Zahra Valedkarimi; Leili Aghebati-Maleki; Jalal Abdolalizadeh; Tohid Kazemi; Mojghan Esparvarinha; Jafar Majidi

Volume 8, Issue 4 , December 2017, , Pages 307-312

  Antibodies are essential tools of biomedical and biochemical researches. Polyclonal antibodies are produced against different epitopes of antigens. Purified F(ab')2 can be used for animal’s immunization to produce polyclonal antibodies. Human immunoglobulin G (IgG) was purified by ion exchange ...  Read More