Document Type : Original Article


1 The aquatic animal health department, Faculty of Veterinary Medicine, Tehran, Iran

2 Department of food hygiene and Quality Control, Faculty of Veterinary Medicine and Artemia & Aquatic Animals Research Institute, Urmia University, Urmia, Iran


The use of various antioxidants to improve fish growth and health has increased in recent years. This study aimed to evaluate the effects of resveratrol antioxidant on improving rainbow trout health by investigating its effects on digestive enzymes, liver enzymes, and biochemical parameters of rainbow trout blood. Accordingly, 225 juvenile rainbow trout with an average body weight of 10 ± 1.5 g were stored in 9 tanks. The study was performed in a completely randomized plan with 3 treatments of 0, 400, and 800 mg of resveratrol antioxidant per kilogram of food with 3 replications. During the experiment, fish were fed based on their body weight percentage using standard feeding tables, and the calculated rations were provided to the fish in 3 meals for 8 weeks. Nine fish were randomly selected from each treatment at the end of the fourth and eighth weeks of the experiment. The present study showed that 800-mg resveratrol treatment significantly increased lipase enzyme activity (31.400 ± 0.322-U/mg protein) compared to the control group (29.922 ± 0.523-U/mg protein) in the eighth week. Also, this treatment of resveratrol in the eighth week significantly increased the amount of high-density lipoprotein (HDL; 123.045 ± 1.570 mg/dL) in the blood compared to the control group (97.055 ± 1.463 mg/dL; P < 0.05). In addition, 800-mg resveratrol treatment effectively reduced alanine aminotransferase (ALT), alkaline phosphatase (ALP), aspartate aminotransferase (AST), glucose, cortisol, and cholesterol (P < 0.05).


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