Veterinary Research Forum
Vet Res Forum

Echocardiographic indices probe during dexmedetomidine/midazolam - ketamine anesthesia in dogs undergoing ovariohysterectomy

Document Type : Original Article

Authors

Anju Poonia 1
Deepak Kumar Tiwari 2
Sandeep Sahara 3
Neeraj Arora 2
Gaurav Kumar 4
Tarun Kumar 3

1 Department of Veterinary Surgery and Radiology, College of Veterinary Sciences, Guru Angad Dev University of Veterinary and Animal Sciences, Ludhiana, India

2 Department of Veterinary Surgery and Radiology, College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, India

3 Department of Veterinary Clinical Complex, College of Veterinary Sciences, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar, India

4 Department of Veterinary Surgery and Radiology, College of Veterinary Sciences, Guru Angad Dev University of Veterinary and Animal Sciences, Rampura Phul, India

https://doi.org/10.30466/vrf.2024.2019897.4130
Abstract
Cardiovascular and respiratory alterations during anesthesia are of major concern in canines. Thus, it is essential to understand the potential depressant effects of anesthetic drugs on cardio-vascular system; so that, anesthetic procedures are conducted in the best possible way. The objective of the study was to assess and compare the echocardiographic indices during dex-medetomidine and midazolam anesthesia in dogs undergoing elective ovariohysterectomy. Twenty-eight female dogs brought to the department for elective ovariohysterectomy were randomly divided into two groups comprising of 14 each. Sedation was achieved with dex-medetomidine and GMID. Physiological parameters and echocardiographic indices were evaluated before drug administration (T0), after 10 min of sedation (T1), after induction (T2) and at the end of surgery (T3) in both groups. Heart rate was significantly higher at T1, T2 and T3; while, rectal temperature was significantly lower at T3 in GMID compared to the GDEX. There was a significant decrease in stroke volume and cardiac output values at T1 and then, a significant increase at T2; whereas, there was a non-significant decrease at T3 in both groups. Ejection fraction and fractional shortening values decreased significantly at T1, increased significantly at T2 and then, decreased significantly at the end of surgery (T3). Dexmedetomidine-ketamine and midazolam-ketamine combinations provide better hemodynamic and respiratory stability in the dogs undergoing elective ovariohysterectomy. Systolic functions were minimally altered with GMID compared to GDEX. Thus, GMID is more cardio stable compared to GDEX.

Keywords

Dexmedetomidine
Dogs
Echocardiography
Ketamine
Midazolam
Subjects
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Veterinary Research Forum
Volume 15, Issue 11
November 2024
Pages 591-597

  • Receive Date 08 January 2024
  • Revise Date 09 April 2024
  • Accept Date 07 May 2024

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