Veterinary Research Forum

A massive cutaneous squamous cell carcinoma in the mammary region of a male Pitbull dog: a clinical report

Articles in Press

Document Type : Clinical Report

Authors

Mehdi Behfar 1
Seyed Mohamad Hashemi-Asl 1
Seyede Soraya Mahmoudi 2
Dara Azizi 1
Mehrdad Rezayi 1
Saba Seyedkhalilollahi 3

1 Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran

2 Department of Pathobiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran

3 DVM Student, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran

https://doi.org/10.30466/vrf.2026.2077302.4985
Abstract
Cutaneous squamous cell carcinoma (CSCC) is a clinically significant skin neoplasm in dogs, typically arising in areas exposed to chronic ultraviolet light. This report described a 10-year-old intact male Pitbull dog weighing 33.00 kg that presented with a large, ulcerated, necrotic and hemorrhagic mass in the inguinal mammary region. Initial hematological evaluation revealed marked leukocytosis with segmented neutrophilia, severe toxic changes along with degenerated neutrophils observed in fine needle aspiration of the mass. Following a course of antibiotic therapy to control the severe infection, the mass was surgically excised using electrosurgery. The preoperative thoracic radiographs ruled out pulmonary metastasis. Histopathological examination confirmed the diagnosis of CSCC. Despite complete initial removal, tumor recurrence was noted seven months postoperatively. The owner declined further chemotherapy and surgical intervention. This report detailed the clinical case of a massive, CSCC located in the ventral abdominal/inguinal mammary region of a male Pitbull dog. Although CSCC is a common neoplasm in canines, this case was distinguished by its extreme size, secondary infection and atypical anatomical presentation in a male dog. The report highlighted the unique clinical challenges associated with managing an unusually severe manifestation of a common tumor and provided a comprehensive overview of the surgical, radiological and histopathological findings.

Keywords

Cutaneous tumor
Dog
Electrosurgery
Squamous cell carcinoma
Subjects
Veterinary Research Forum

Articles in Press, Accepted Manuscript
Available Online from 31 August 2026

  • Receive Date 09 November 2025
  • Revise Date 24 February 2026
  • Accept Date 11 July 2026

Home

Guide for Authors

Submit Manuscript

Reviewers

Contact Us