Veterinary Research Forum
Vet Res Forum

Histopathological lesions of Actinobacillus pleuropneumoniae serotype 8 in infected pigs

Document Type : Short Communication

Authors

Vasileios Georgios Papatsiros 1
Ioanna Stylianaki 2
Constantina Nikolaos Tsokana 1
Georgios Papakonstantinou 1
Marios Christophorou 3
Nikolaos Papaioannou 2
Labrini Vasileios Athanasiou 1

1 Clinic of Medicine, Faculty of Veterinary Medicine, School of Health Sciences, University of Thessaly, Karditsa, Greece

2 Laboratory of Pathology, Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece

3 Private Veterinary Clinic, Nicosia, Cyprus

https://doi.org/10.30466/vrf.2022.556971.3539
Abstract
This study aimed to report, for the first time, histopathological lesions caused by an outbreak of acute Actinobacillus pleuropneumoniae serotype 8 infections in two farms in Cyprus. Lung tissue samples were collected from two different affected farms (a total of eight samples) for bacterial culture, multiplex polymerase chain reaction (PCR)-based serotyping and histopathological evaluation. Severe respiratory clinical signs, vomiting, anorexia, sudden deaths, a morbidity rate of around 25.00% and a mortality rate of over 60.00% in the fattening stage were reported. Macroscopic lesions included acute to subacute fibrotic, hemorrhagic and necrotizing pneumonia with occasionally encapsulated nodule-like abscesses and fibrous pleuritis. Histopathological evaluation revealed fibrous exudate between alveolar spaces and connective tissue, areas of necrosis mixed with alveolar macrophages, lymphocytes, plasma cells and necrotic leukocytes surrounding colonies of cocci. The bronchial and bronchiolar epithelia were degenerated and replaced by eosinophilic cell debris mixed with inflammatory cells. Several arteries and capillaries were clotted and/or infiltrated by inflammatory cells. In conclusion, these A. pleuropneumoniae serotype 8 cases were accompanied by acute illness, death and more pronounced bronchitis and bronchiolitis.

Keywords

Actinobacillus pleuropneumoniae
Histopathology
Pig
Respiratory lesions
Serotype 8

Subjects

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Veterinary Research Forum
Volume 14, Issue 7
July 2023
Pages 401-404

  • Receive Date 01 July 2022
  • Revise Date 05 September 2022
  • Accept Date 16 October 2022

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