Calculation of Intracranial Volume in Koçeri Sheep by CT scan and Cavalieri Principle

Document Type : Original Article

Authors

1 Department of Laboratory and Veterinary Health, Technical Science Vocational High School, Batman University, Batman, Turkey

2 Department of Anatomy, Faculty of Veterinary Medicine, Bingöl University, Bıngol, Turkey

3 Department of Anatomy, Faculty of Veterinary Medicine, Selcuk University, Konya, Turkey

10.30466/vrf.2025.2060783.4764
Abstract
The calculation of the cranial cavity volume is important for brain development, pathologies, and health status. In recent years, advancements in clinical applications have made volume calculation methods from radiological images more consistent. In this context, it was aimed to calculate the intracranial volume of the Koçeri sheep's skulls using 3D models based on computed tomography scan (CT scan) sections and stereology. In the study, 7 adult female and 7 male Koçeri sheep were used. The skulls used were scanned with a 64-detector Multi-Detector Computed Tomography device with a section thickness of 0.625 mm, 80 kV, 200 mA, and 639 mGy specifications. Using the MIMICS 20.1 software, three-dimensional models of the skull region were created and intracranial volumes were measured. The same reference points were measured using the Cavalieri principle. As a result of the study, measurements taken using CT scan showed that the cranial volume in females was 133.09 ± 7.81 cm³ and in males was 148.68 ± 16.25 cm³. The intracranial volume calculated using the Cavalieri principle was found to be 133.87 ± 8.43 cm³ in females and 149.77 ± 16.74 cm³ in males. The data were statistically analyzed in terms of two methods and sexual dimorphism. While no difference was found between the methods, a significant statistical difference was determined between the genders. In this context, our study is believed to make significant contributions to clinical sciences through accurate management of cranial disease diagnosis and processes, and to taxonomy through identification of interspecies differences.

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Articles in Press, Accepted Manuscript
Available Online from 06 June 2026

  • Receive Date 16 May 2025
  • Revise Date 05 November 2025
  • Accept Date 10 December 2025