Volume 15 (2024)
Volume 14 (2023)
Volume 13 (2022)
Volume 12 (2021)
Volume 11 (2020)
Volume 10 (2019)
Volume 9 (2018)
Volume 8 (2017)
Volume 7 (2016)
Volume 6 (2015)
Volume 5 (2014)
Volume 4 (2013)
Volume 3 (2012)
Volume 2 (2011)
Volume 1 (2010)
Evaluation of di-n-butyl phthalate reproductive toxicity in pregnant rats and their offspring and assessment of vitamin E administration in reducing toxicity

Toktam Heidari; Rooz Ali Batavani; Hassan Malekinejad; Rahim Hobbenaghi

Volume 13, Issue 2 , June 2022, , Pages 201-208

  Phthalates are environmental contaminants mostly used as plasticizers and additives in different products. Having endocrine-disrupting properties, phthalates are known as potential reproductive toxicants. The present study was conducted to evaluate the reproductive toxicity of di-n-butyl phthalate (DBP) ...  Read More

Mycotoxicoses in veterinary medicine: Aspergillosis and penicilliosis

Hassan Malekinejad; Johanna Fink-Gremmels

Volume 11, Issue 2 , June 2020, , Pages 97-103

  Molds and mycotoxins are contaminants of animal feed causing spoilage and clinical intoxication. Animal exposure to mycotoxins reflects diet composition with major differences occurring between animals kept predominantly of pastures, i.e. ruminants and horses, and those consuming formulated feed like ...  Read More

Alpha-zearalenol negatively influences ram sperm parameters during liquid storage

Soghra Abbaszadeh; Farhad Farrokhi-Ardabili; Hassan Malekinejad; Iraj Bernousi

Volume 9, Issue 2 , June 2018, , Pages 171-178

  This study was aimed to investigate the effects of 17 𝛽-estradiol (E2) and 𝛼-zearalenol (α-ZOL) on motility parameters, plasma membrane integrity, levels of produced nitric oxide (NO) and total antioxidant capacity of Ghezel ram sperm during the liquid storage at 4 ˚C, for various periods ...  Read More

Antioxidant effects of Spirulina platensis (Arthrospira platensis) on ‎cyclophosphamide-induced testicular injury in rats

Mohammad Afkhami-Ardakani; Shapour Hasanzadeh; Rasoul Shahrooz; Norouz Delirezh; Hassan Malekinejad

Volume 9, Issue 1 , March 2018, , Pages 35-41

  Cyclophosphamide (CP) is known to reduce fertility. The protective effects of Spirulina plantesis (SP) against CP-induced testicular toxicity were investigated. Male Wistar rats were categorized into eight groups (n = 7). Four groups of rats were administered CP at a dose of 5 mg in 5 mL distilled water ...  Read More

Clinical Pathology
Anti-atherosclerotic effect of Cynodon dactylon extract on experimentally induced hypercholesterolemia in rats

Belal Pashaie; Rahim Hobbenaghi; Hassan Malekinejad

Volume 8, Issue 3 , September 2017, , Pages 185-193

  Cynodon dactylon (Bermuda grass) is a perennial plant traditionally used as an herbal medicine in many countries. In the present study, anti-atherosclerotic property of ethanolic extract of C. dactylon was investigated in the experimentally induced hypercholesterolemia in rats. In this study, 36 male ...  Read More

Small Animal Surgery
Evaluation of tendon healing using fibroblast like synoviocytes in rabbits: A biomechanical study

Mahboobeh Azad-Tirgan; Farshid Sarrafzadeh-Rezaei; Hassan Malekinejad; Rahim Hobbenaghi; Behnam Heshmatian

Volume 7, Issue 1 , March 2016, , Pages 21-26

  Tendon never restores the complete biological and mechanical properties after healing. Several techniques are available for tissue-engineered biological augmentation for tendon healing like stem cells. Recently, synovium has been investigated as a source of cells for tissue engineering. In the present ...  Read More

Protective effect of ethyl pyruvate on mice sperm parameters in phenylhydrazine induced hemolytic anemia

Ali Akbar Mozafari; Rasoul Shahrooz; Abbas Ahmadi; Hassan Malekinjad; Karim Mardani

Volume 7, Issue 1 , March 2016, , Pages 63-68

  The aim of the present study was to assess the protective effect of ethyl pyruvate (EP) on sperm quality parameters, testosterone level and malondialdehyde (MDA) in phenylhydrazine (PHZ) treated mice. For this purpose, 32 NMRI mice with the age range of 8 to 10 weeks, weight average 26.0 ± 2.0 ...  Read More

Clinical Pathology
Fructooligosaccharide raftilose reduces the mycophenolate mofetil-induced complications: Hematological and biochemical alterations

Hadi Cheraghi; Zohreh Khaki; Hassan Malekinejad; Farhang Sasani

Volume 6, Issue 4 , December 2015, , Pages 319-326

  Mycophenolate mofetil (MMF) is a selective inhibitor of Inosine-5′-monophosphate dehydrogenase. Gastrointestinal (GI) disturbances in immature ones are reported for MMF-induced compilations, which in the case of occurrence dose reduction is required. Thus, in the present study, the fructooligosaccharide ...  Read More

The role of sera from equine grass sickness on apoptosis induction in PC12 Tet-off p53 cell line

Hassan Malekinejad; Nazli Alizadeh-Tabrizi; Araz Ostadi; Johanna Fink-Gremmels

Volume 6, Issue 1 , March 2015, , Pages 9-15

  The pathogenesis of equine grass sickness (EGS) has not fully understood. A better understanding of the exact pathogenesis of diseases can help to make an accurate diagnosis. Previous studies reported some pathological damage of neuronal cells in EGS patients. In this study, primarily cytotoxicity of ...  Read More

Protective effects of cornus mas extract on in vitro fertilization potential in methotrexate treated male mice

Leila Zarei; Rasoul Shahrooz; Rajabali Sadrkhanlou; Hassan Malekinejad; Abbas Ahmadi; Zahra Bakhtiary

Volume 6, Issue 1 , March 2015, , Pages 55-61

  Current study was aimed to evaluating protective effects of cornus mas fruit extract (CMFE) in mice treated with methotrexate (MTX). For this purpose, 48 young mature male mice were divided into 6 groups. Control group received only normal saline (0.1 mLper day, intraperitoneally), and the second group ...  Read More

Protective effects of vitamin E and Cornus mas fruit extract on methotrexate-induced cytotoxicity in sperms of adult mice

Leila Zarei; Rajabali Sadrkhanlou; Rasoul Shahrooz; Hassan Malekinejad; Behroz Eilkhanizadeh; Abbas Ahmadi

Volume 5, Issue 1 , March 2014, , Pages 21-27

  This study was aimed to assess the protective effects of Cornus mas fruit extract (CMFE) and vitamin E (Vit E) on sperm quality parameters in the methotrexate (MTX)-treated mice. Forty-eight young adult male mice (8-12 weeks) were randomly divided into six groups including control and test groups. The ...  Read More

Adverse effects of long-time exposure to formaldehyde vapour on testicular tissue and sperm parameters in rats

Mazdak Razi; Hassan Malekinejad; Reza Sayrafi; Mohammad Reza Hosseinchi; Sajad Feyzi; Seyed Mehdi Moshtagion; Hamed Janbaz

Volume 4, Issue 4 , December 2013, , Pages 213-219

  Formalin is widely used in industry and in medicine (as tissue fixative and disinfectant).It contains reactive molecules which have been known for its cytotoxic effects. To evaluate the effect of formalin exposure on the testicular tissue and sperm parameter from neonatal period through physical and ...  Read More

Mycophenolate mofetil alters the antioxidant status in duodenum of rats: Implication for silymarin usage in mycophenolate mofetil-induced gastrointestinal disorders

Sanaz Sheikhzadeh; Hassan Malekinejad; Rahim Hobbenaghi

Volume 4, Issue 2 , June 2013, , Pages 77-83

  Mycophenolate mofetil (MMF) as an immunosuppressive agent is used to prevent graft rejection. One of the adverse effects of long time administration of MMF is the gastrointestinal disorder. This study aimed to investigate the gastroprotective effect of silymarin (SMN) on MMF-induced gastrointestinal ...  Read More

Atrazine in sub-acute exposure results in sperm DNA disintegrity and nuclear immaturity in rats

Sajad Feyzi-Dehkhargani; Rasoul Shahrooz; Hassan Malekinejad

Volume 3, Issue 1 , March 2012, , Pages 19-26

  This study was designed to evaluate the detrimental effect of atrazine (ATR) on germinal epitheliums (GE) cytoplasmic carbohydrate (CH) and unsaturated fatty acids (UFA) ratio and to clarify the effect of ATR on serum levels of FSH, LH, testosterone and inhibin-B (INH-B). The impact of ATR exposure on ...  Read More

Chemoprotective effect of Crataegus monogyna aqueous extract against cyclophosphamide-induced reproductive toxicity

Ali Shalizar Jalali; Shapour Hassanzadeh; Hassan Malekinejad

Volume 2, Issue 4 , December 2011, , Pages 266-273

  Cyclophosphamide (CP) is extensively used as an antineoplastic agent for treatment of various cancers, as well as an immunosuppressive agent. However, despite its wide spectrum of clinical uses, CP is known to cause several adverse effects including reproductive toxicity in humans and experimental animals. ...  Read More

Histological Impact of Long Term Varicocele-Induction on Right and Left Testes in Rat (Evidence for the Reduction of Sperm Quality and Mating Abilities)

Mazdak Razi; Hassan Malekinejad; Rajab-Ali Sardkhanlou; Farshid Sarrafzadeh-Rezaei

Volume 2, Issue 3 , September 2011, , Pages 189-201

  This study was designed to clarify bilaterally effect of long-time varicocele on left and right testes and to identify the effect of varicocele on maturation divisions during spermatogenesis. Moreover, the percentage of seminiferous tubules (STs) with I-VIII and IX-XIV stages of spermatogenesis and sperm ...  Read More

The Protective Effect of Liquorice Plant Extract on CCl4-Induced Hepatotoxicity in Common Carp (Cyprinus carpio)

Hassan Malekinejad; Arash Alizadeh; Hadi Cheraghi; Saeed Meshkin; Fereshteh Dardmeh

Volume 1, Issue 3 , December 2010, , Pages 158-164

  The protective effect of liquorice plant extract (LPE) on CCl4-induced hepatotoxicity in common carp was evaluated using fifty adult carps. The fish were cultured in a standard environment in terms of water flow rate, oxygen, pH, food and temperature. The fish were assigned into 5 groups (N = 10) as ...  Read More