Volume 15 (2024)
Volume 14 (2023)
Volume 13 (2022)
Volume 12 (2021)
Volume 11 (2020)
Volume 10 (2019)
Volume 9 (2018)
Volume 8 (2017)
Volume 7 (2016)
Volume 6 (2015)
Volume 5 (2014)
Volume 4 (2013)
Volume 3 (2012)
Volume 2 (2011)
Volume 1 (2010)
The effects of pomegranate extract on normal adult rat kidney: A stereological study

Esrafil Mansouri; John Basgen; Sadegh Saremy

Volume 7, Issue 1 , March 2016, , Pages 1-6

  Pomegranate (Punica granatum L.) has been used widely in the traditional medicine of various civilizations for more than 5000 years. The pomegranate tree has several parts; each part has useful medicinal effects. Previous studies have demonstrated the antibacterial, antioxidant, and anti-inflammatory ...  Read More

Busulfan induced azoospermia: Stereological evaluation of testes in rat

Mohadeseh Panahi; Saeideh Keshavarz; Farhad Rahmanifar; Amin Tamadon; Davood Mehrabani; Negar Karimaghai; Masood Sepehrimanesh; Heydar Aqababa

Volume 6, Issue 4 , December 2015, , Pages 273-278

  The aim of the present study was stereological evaluation of testes of azoospermic animal model using busulfan in rat. Three groups of male adult rats were used in this study. The first group was injected by single dose of busulfan (10 mg kg-1) and their testes were removed on day 35 post injection. ...  Read More

Clinical Pathology
The anti-inflammatory and anti-apoptotic effects of gallic acid against mucosal inflammation- and erosions-induced by gastric ischemia-reperfusion in rats

Seyyed Ali Mard; Shahnaz Mojadami; Yaghoob Farbood; Mohammad Kazem Gharib Naseri

Volume 6, Issue 4 , December 2015, , Pages 305-311

  The present study aimed to evaluate the protective effect of gallic acid on gastric mucosal lesions caused by ischemia-reperfusion (I/R) injury in rat. Forty male rats were randomly divided into sham, control (I/R injury) and three gallic acid-pretreated groups. To induce I/R lesions, the celiac artery ...  Read More

Evaluation of the anti-nociceptive effects of morphine, tramadol, meloxicam and their combinations using the tail-flick test in rats

Mehrzad Foroud; Nasser Vesal

Volume 6, Issue 4 , December 2015, , Pages 313-318

  The purpose of the present study was to evaluate anti-nociceptive effects of morphine, tramadol, meloxicam and their combinations in rats. Seventy male Wistar rats were divided into seven equal groups and randomly assigned to receive intraperitoneal saline (S) (control group, 1.0 mL kg-1), morphine (MO) ...  Read More

Stem Cells
In vitro histological investigation of interactions between rat decellularized large intestine scaffold and human adipose derived mesenchymal stem cells

Somayeh Naderi; Malihe Akbarzadeh Niaki; Nasser Mahdavi Shahri; Maryam Moghaddam Matin; Masoud Fereidoni; Fatemeh Naseri

Volume 6, Issue 3 , September 2015, , Pages 251-255

  The aim of this study was to investigate the interactions between rat intestine decellularized scaffold and human adipose derived mesenchymal stem cells. Rat large intestine was dissected in fragments and decellularized by physicochemical methods. The scaffolds were loaded by human adipose derived mesenchymal ...  Read More

Changes of stress oxidative enzymes in rat mammary tissue, blood and milk after experimental mastitis induced by E. coli lipopolysaccharide

Hadi Eslami; Rooz Ali Batavani; Siamak Asr‎i-Rezaei; Rahim Hobbenaghi

Volume 6, Issue 2 , June 2015, , Pages 131-136

  The present study investigated the effects of E. coli lipopolysaccharide (LPS) induced mastitis model in rat on the activity of antioxidant enzyme systems. To achieve this purpose, E. coli LPS were infused into the mammary gland of 12 rats 72 hr postpartum and compared with 12 rats in control group infused ...  Read More

The histological and histometrical effects of Urtica dioica extract on rat’s prostate hyperplasia

Hamid Reza Moradi; Naeem Erfani Majd; Saleh Esmaeilzadeh; Sayed Reza Fatemi Tabatabaei

Volume 6, Issue 1 , March 2015, , Pages 23-29

  Benign prostatic hyperplasia (BPH) is a common disease in human that gradual overgrowth of the prostate gland leads to impinge on the urethra with impairment in urinary function. Numerous plants improve uncontrolled growth of the prostate gland and improve urinary tract symptoms associated with BPH. ...  Read More

Histomorphometric changes of small intestine in pregnant rat

Fatemeh Sabet Sarvestani; Farhad Rahmanifar; Amin Tamadon

Volume 6, Issue 1 , March 2015, , Pages 69-73

  Food intake of rats increases during pregnancy. This requires changes in the structure of the small intestine to absorb additional food. The aim of the present study was to investigate the morphological changes in the layers of small intestine in rats during pregnancy. Duodenum, jejunum and ileum of ...  Read More

Protective effects of pomegranate seed oil on ovariectomized rats as a model of postmenopausal osteoporosis: A multi-detector computed tomography evaluation

Morteza Saravani; Hossein Kazemi Mehrjerdi; Ali Mirshahi; Amir Afkhami Goli

Volume 5, Issue 4 , December 2014, , Pages 263-267

  The pomegranate seed oil (PSO), containing 17-α-estradiol, is one of the newly found phytosterols with synergistic health effects on estrogen related physiological conditions. Herein, PSO was assessed for its potential improving effects on bone characteristics in a rat model of menopausal syndrome. ...  Read More

Protective effects of garlic aquous extract (Allium sativum), vitamin E, and N-acetylcysteine on reproductive quality of male rats exposed to lead

Reza Asadpour; Mehdi Azari; Marzie Hejazi; Hossein Tayefi; Neda Zaboli

Volume 4, Issue 4 , December 2013, , Pages 251-257

  The objective of present study was to investigate the effects of aqueous garlic extracts, vitamin E and N-acetylcysteine on lead-induced lipid peroxidation, changes in antioxidant defense system and semen quality in the rat testes. Twenty-five male rats were divided into five groups. Animals within different ...  Read More

Effect of gibberellic acid on the quality of sperm and in vitro fertilization outcome in adult male rats

Mohammadreza Hosseinchi; Farhad Soltanalinejad; Gholamreza Najafi; Leila Roshangar

Volume 4, Issue 4 , December 2013, , Pages 259-264

  Gibberellic acid (GA3) is a group of plant hormones identified in various plants. The aim of this study was to determine the effects of GA3 on sperm parameters and in vitro fertilization (IVF). Fifty six adult male rats were divided into seven groups as, control, treatment and sham. Following 15, 30 ...  Read More

Effect of curcumin on rat sperm morphology after the freeze-thawing process

Ali Soleimanzadeh; Adel Saberivand

Volume 4, Issue 3 , September 2013, , Pages 185-189

  Reactive oxygen species (ROS) generation, induced by the cryopreservation process, can be responsible for mammalian sperm damage. Curcumin is known as an effective antioxidant against oxidative stress. The aim of this study was to evaluate the effects of curcumin on sperm count, motility and viability, ...  Read More

An investigation on body weights, blood glucose levels and pituitary-gonadal axis hormones in diabetic and metformin-treated diabetic female rats

Pouya Pournaghi; Rajab-Ali Sadrkhanlou; Shapour Hasanzadeh; Azadeh Foroughi

Volume 3, Issue 2 , June 2012, , Pages 79-84

  Diabetes is a metabolic disorder which affects whole body systems including reproductive system. Diabetes is also a contributing factor to infertility. Metformin is one of the most common drugs to control hyperglycemia. In this study, 36 adult Sprague-Dawley female rats (170-210 g) were divided into ...  Read More

Effect of pilocarpine on the formalin-induced orofacial pain in rat

Esmaeal Tamaddonfard; Amir Erfanparast; Emad Khalilzadeh

Volume 3, Issue 2 , June 2012, , Pages 91-95

  In this study, the effects of subcutaneous (SC) injection of pilocarpine (a cholinomimetic agent) and atropine (a muscarinic receptors antagonist) were investigated on a tonic model of orofacial pain in rats. The contribution of the endogenous analgesic opioid system was assessed using naloxone (an opioid ...  Read More

The Histological, Histomorphometrical and Histochemical Changes of Testicular Tissue in the Metformin Treated and Untreated Streptozotocin-Induced Adult Diabetic Rats

Davoud Kianifard; Rajab-Ali Sadrkhanlou; Shapour Hasanzadeh

Volume 2, Issue 1 , March 2011, , Pages 13-24

  In this investigation, diabetes was induced in adult male Sprague-Dawley rats by single intraperitoneal injection of streptozotocin (STZ) at 45 mg kg-1 of body weight. A group comprised of 8 diabetic rats was treated with metformin at 100 mg kg-1 of body weight for reducing the elevated blood glucose ...  Read More

Bridging Small-Gap Peripheral Nerve Defect Using Silicone Rubber Chamber in the Rat Sciatic Nerve Transection Model

Saeed Azizi; Rahim Mohammadi; Keyvan Amini; Roza Fallah; Kiana Karegar

Volume 1, Issue 2 , September 2010, , Pages 107-115

    Despite promising results observed using silicone rubber chamber, no previous comprehensive work was performed on behavior of the conduit. Present study aimed at further functional, histomorphometrical and immunohistochemical assessment of nerve regeneration in the same animal along a 10-mm rat ...  Read More