Volume 15 (2024)
Volume 14 (2023)
Volume 13 (2022)
Volume 12 (2021)
Volume 11 (2020)
Volume 10 (2019)
Volume 9 (2018)
Volume 8 (2017)
Volume 7 (2016)
Volume 6 (2015)
Volume 5 (2014)
Volume 4 (2013)
Volume 3 (2012)
Volume 2 (2011)
Volume 1 (2010)
Effect of nanocurcumin on fertility in murine model of polycystic ovary syndrome

Zahra Aaly-Gharibeh; Mohammadreza Hosseinchi; Ali Shalizar-Jalali

Volume 15, Issue 2 , February 2024, , Pages 113-117

  The precise pathophysiology of polycystic ovary syndrome (PCOS) is not well-founded. In an attempt to fill this gap, the current study was executed to probe the effect of nanocurcumin (NCC) on ovarian tissue, in vitro fertilization (IVF) and pre-implantation embryo development in a mouse model of PCOS. ...  Read More

The comparative effects of estrogen and tacrolimus on crushed sciatic nerve regeneration in male mice: functional and histological evaluation

Fereshteh Farahani; Hamidreza Fattahian; Ahmad Asghari; Pejman Mortazavi

Volume 13, Issue 2 , June 2022, , Pages 241-247

  Some pharmacological agents can be effective for peripheral nerve injuries treatments. Present study aimed to apply different agents and compare the nerve regenerative effects following crushed sciatic nerve injuries. Twenty four (n=24) adult male mice were conducted in this study. Standard unilateral ...  Read More

Gold nanoparticles improve the embryonic developmental competency of artificially activated mouse oocytes

Tahir Muhammad; Muhammad Ameen Jamal; Muhammad Ashraf; Nosheen Zafar; Shamaila Shahzadi; Tahir Maqbool; Faheem Hadi; Riaz Amjad

Volume 12, Issue 4 , December 2021, , Pages 415-420

  Currently, artificial oocyte activation has attracted wide attention in assisted reproduction due to extensive range of applications, particularly in somatic cell nuclear transfer and deriving pluripotent stem cell lines and it is the unique model to determine the role of paternal genome. Numbers of ...  Read More

Possible protective effects of crocin on destructive side effects of cyclo-phosphamide in mice ovarian tissue: Evaluation of histomorphometrical and biochemical changes

Fahimeh Khanmohammadi; Rasoul Shahrooz; Abbas Ahmadi; Mazdak Razi

Volume 12, Issue 2 , June 2021, , Pages 217-222

  One of the side effects of cyclophosphamide (CP) is low fertility. In this study, we investigated the protective role of crocin (Cr) against CP chemotherapy-induced changes in ovarian tissue. In the current study, we treated 15 female mice aged 6-8 weeks old for 21 days. The mice were distributed into ...  Read More

Protective effect of ethyl pyruvate on testicular histology and fertilization potential in cyclophosphamide treated mice

Zahra Bakhtiary; Rasoul Shahrooz; Abbas Ahmadi; Farhad Soltanalinejad

Volume 11, Issue 1 , March 2020, , Pages 7-13

  In the present study, we aimed to address the use of ethyl pyruvate (EP) against the harmful effects of cyclophosphamide (CP) treatment. Thirty-nine adult male mice were divided into three groups including control group received normal saline [0.20 mL per day; intraperitoneally (IP)], CP group received ...  Read More

The effects of exposure to fluoxetine during lactation on testicular tissue and sperm parameters in mice offspring

Mojtaba Karimi pour; Abbas Ahmadi; Masoumeh Zirak Javanmard; Abass Jafari; Maryam Mohebi; Elnaz Hosseinalipour

Volume 11, Issue 1 , March 2020, , Pages 35-42

  Fluoxetine is a selective serotonin reuptake inhibitor is commonly prescribed to treat maternal depression in pregnancy and lactation. This study aimed to investigate the effects of maternal exposure to fluoxetine via lactation on testicular tissue, sperm parameters including count, motility, viability, ...  Read More

Protective effects of Cornus Mas fruit extract on methotrexate-induced alterations in mice testicular tissue: Evidences for histochemical and histomorphometrical changes in an animal model study

Leila Zarei; Rasoul Shahrooz

Volume 10, Issue 4 , December 2019, , Pages 307-313

  Methotrexate (MTX) as a chemotherapeutic agent, has adverse effects on reproductive organs by enhancing oxidative stress. In this study, the protective effects of Cornus mas fruit extract (CMFE) against MTX side effects were evaluated. Forty-eight mature male NMRI mice were divided into six groups: group ...  Read More

Royal jelly protects male mice against nicotine-induced reproductive failure

Farnam Azad; Vahid Nejati; Ali Shalizar-Jalali; Gholamreza Najafi; Fatemeh Rahmani

Volume 9, Issue 3 , September 2018, , Pages 231-238

  This study evaluated the possible protective effect of royal jelly (RJ) on sperm parameters and sperm malondialdehyde (MDA) concentration and in vitro fertilizing potential in nicotine (NIC) exposed male mice. Thrtiy-six male BALB/c mice were randomly divided into six groups (n = 6). Group 1 received ...  Read More

Ameliorative effect of Allium sativum extract on busulfan-induced oxidative stress in mice sperm

Ali Soleimanzadeh; Leila Mohammadnejad; Abbas Ahmadi

Volume 9, Issue 3 , September 2018, , Pages 265-271

  Busulfan is known to cause several adverse effects including reproductive toxicity in humans. Garlic (Allium sativum), a widely distributed medicinal plant, is highly regarded for its medicinal activities including antioxidant property.This study was conducted to assess whether garlic extract could serve ...  Read More

Expression of pluripotent stem cell markers in mouse uterine tissue during estrous cycle

Kolsum Choobineh; Saeed Zavareh; Mojdeh Salehnia; Mohamad Taghi Ghorbanian; Seyed Hassan paylakhi

Volume 7, Issue 3 , September 2016, , Pages 181-188

  It was assumed that uterine stem cells are responsible for the unique regenerative capacity of uterine. Therefore, the aim of the present study was to investigate the expression of the pluripotent stem cell markers in the mice uterine tissue during different stages of estrous cycles. Twelve virgin female ...  Read More

Androgen receptor blockade using flutamide skewed sex ratio of litters in mice

Faramarz Gharagozlou; Reza Youssefi; Mehdi Vojgani; Vahid Akbarinejad; Ghazaleh Rafiee

Volume 7, Issue 2 , June 2016, , Pages 169-172

  Maternal testosterone has been indicated to affect sex ratio of offspring. The present study was conducted to elucidate the role of androgen receptor in this regard by blockade of androgen receptor using flutamide in female mice. Mice were randomly assigned to two experimental groups. Mice in the control ...  Read More

Protective effects of cornus mas extract on in vitro fertilization potential in methotrexate treated male mice

Leila Zarei; Rasoul Shahrooz; Rajabali Sadrkhanlou; Hassan Malekinejad; Abbas Ahmadi; Zahra Bakhtiary

Volume 6, Issue 1 , March 2015, , Pages 55-61

  Current study was aimed to evaluating protective effects of cornus mas fruit extract (CMFE) in mice treated with methotrexate (MTX). For this purpose, 48 young mature male mice were divided into 6 groups. Control group received only normal saline (0.1 mLper day, intraperitoneally), and the second group ...  Read More

Evaluation of antioxidant effects of crocin on sperm quality in cyclophosphamide treated adult mice

Zahra Bakhtiary; Rasoul Shahrooz; Abbas Ahmadi; Leila Zarei

Volume 5, Issue 3 , July 2014, , Pages 213-218

  Cyclophosphamide (CP) is one of the anti-neoplastic drugs. Despite its numerous clinical applications, it has devastating effects on the testicles and declines the sperm quality in treated patients. This study was aimed to investigate the protective effect of crocin in improving the toxicity induced ...  Read More

A survey on helminthic infection in mice (Mus musculus) and rats (Rattus norvegicus and Rattus rattus) in Kermanshah, Iran

Norollah Pakdel; Soraya Naem; Farid Rezaei; Abdol-Ali Chalehchaleh

Volume 4, Issue 2 , June 2013, , Pages 105-109

  Parasitic infections of rodents can compromise scientific research as well as the health of the animals and humans. Based on previous studies, infection rate of parasitic helminths is different in various regions of Iran. The current survey was aimed to determine endoparasitic helminths infection in ...  Read More

The effect of ciprofloxacin on sperm DNA damage, fertility potential and early embryonic development in NMRI mice

Fatemeh Zobeiri; Rajab-Ali Sadrkhanlou; Siamak Salami; Karim Mardani; Abbas Ahmadi

Volume 3, Issue 2 , June 2012, , Pages 131-135

  Side effects of ciprofloxacin (CPFX), a widely used broad spectrum antibiotic with fluoroquinolone core, have been reported in different organs. In the present study we sought to elucidate the impact of ciprofloxacin on sperm chromatin integrity and sperm DNA damage using Aniline Blue and Acridine Orange ...  Read More

Histopathologic and biochemical assessment of mice ovarian tissue, following experimentally induced copper poisoning

Ehsanollah Sakhaee; Homayoon Babaei; Jalil Abshenas; Omid Azari; Reza Kheirandish; Farideh Ebrahimi-Meymand

Volume 2, Issue 4 , December 2011, , Pages 232-237

  In this study we investigated histopathological changes of mice ovarian tissues following long-term administration of copper sulfate and induction of chronic copper poisoning. The study comprised of three different groups of twenty one mice as follows: The first group (Group 100) which treated by gavage ...  Read More

The effects of green tea (Camellia sinensis) extract on mouse semen quality after scrotal heat stress

Jalil Abshenas; Homayoon Babaei; Mohammad-Hossein Zare; Asie Allahbakhshi; Fariba Sharififar

Volume 2, Issue 4 , December 2011, , Pages 242-247

  The objective of this study was to investigate whether or not the adverse effects of heat on sperm quality could be prevented by green tea extract (GTE) administration. Ninety adult male mice were randomly divided to two groups. The scrotum of each animal in the first group was immersed once for 20 min ...  Read More