Volume 14 (2023)
Volume 13 (2022)
Volume 12 (2021)
Volume 11 (2020)
Volume 10 (2019)
Volume 9 (2018)
Volume 8 (2017)
Volume 7 (2016)
Volume 6 (2015)
Volume 5 (2014)
Volume 4 (2013)
Volume 3 (2012)
Volume 2 (2011)
Volume 1 (2010)
Effect of Saponin on spermatogenesis and testis structure in streptozotocin-induced diabetic mice

Sadigheh Pashapour; Adel Saberivand; Amir Afshin Khaki; Maryam Saberivand

Articles in Press, Accepted Manuscript, Available Online from 08 August 2023

  About a third of human infertility is related to male factors. Of these, idiopathic-related infertility is not curable. Diabetes mellitus is a metabolic disorder that affects male impotence and fertility by increased production of free radicals and oxidative stress. Saponin, a glycosidic compound found ...  Read More

Effects of adenosine N1-Oxide and pioglitazone on inflammatory and antioxidant state in sepsis caused by experimental cecal puncture in rat

Yaser Jafari- Khataylou; Siamak Kazemi-Darabadi; Somayeh Ahmadi Afshar

Volume 14, Issue 7 , July 2023, , Pages 381-387

  Sepsis is an acute condition caused by the systemic inflammatory response syndrome to an infection. There are very few drugs that could improve the severe conditions in patients with sepsis. Hence, it is important to consider different treatment options. In this survey, we studied the effect of adenosine ...  Read More

Effect of crocin on experimental gastrocnemius muscle ischemia/reperfusion injury in rat

Betul Apaydin Yildirim; Selcuk Albayrak

Volume 14, Issue 4 , April 2023, , Pages 201-206

  Ischemia-reperfusion (IR) injury to the lower extremities causes damage to various tissues, notably the limbs. Because research in recent years have demonstrated that saffron and its components are useful in ischemic strokes, the goal of this study was to see whether Crocin (Cr), one of the active constituents ...  Read More

Evaluation of hematological changes, oxidant/antioxidant status and immunological responses in sheep and goats naturally infected with Linguatula serrata

Alireza Alborzi; Mandana Hosseini; Somayeh Bahrami; Masoud Ghorbanpoor; Mohammad Reza Tabandeh

Volume 14, Issue 3 , March 2023, , Pages 161-167

  Linguatula serrata is a worldwide zoonotic food-borne parasite. The parasite is responsible for linguatulosis and poses a concern to human and animal health in endemic regions. This study investigated the hematological changes, oxidant/antioxidant status and immunological responses ...  Read More

Effect of chlorogenic acid on follicular development, hormonal status and biomarkers of oxidative stress in rats with polycystic ovary syndrome

Neda Abedpour; Masoumeh Zirak Javanmard; Mojtaba Karimipour; Amirreza Pourmajed Liqvan

Volume 13, Issue 4 , December 2022, , Pages 513-520

  Polycystic ovarian syndrome (PCOS) is a complex endocrine and metabolic disorder. Chlorogenic acid (CGA) bears antioxidant properties with protective effects on different tissues. This study was conducted to evaluate the effect of CGA on follicular development, hormonal status and biomarkers of oxidative ...  Read More

Effects of Ribes khorasanicum hydro-ethanolic extract on streptozotocin -induced diabetic complications in rats

Zahra Gholamnezhad; Mousa-Al-Reza Hadjzadeh; Reyhaneh Sotoudeh; Azita Aaghaei; Narges Kasraie

Volume 12, Issue 4 , December 2021, , Pages 459-465

  The anti-diabetic effects of Ribes khorasanicum as a traditional remedy were investigated in diabetic rats. Thirty-five male rats were divided into five groups: control, diabetic, diabetic treated with metformin (300 mg kg-1; D+Met), diabetic treated with 250 and 500 mg kg-1 of Ribes khorasanicum hydro-ethanolic ...  Read More

Effects of nano-manganese on humoral immune response and oxidative stress in broilers

Sepideh Sabaghi; Jamshid Razmyar; Mohammad Heidarpour

Volume 12, Issue 4 , December 2021, , Pages 487-491

  The objective of the present study was to evaluate the alterations in selected indicators of immune responses and oxidative stress of broilers fed with nano-manganese. One hundred-sixty 1-day-old broiler chicks were randomly assigned into four groups with three replicates. Birds were fed the same basal ...  Read More

Pro-oxidant and degenerative effects of haloperidol under inflammatory conditions in rat; the involvement of SIRT1 and NF-κB signaling pathways

Saman Bahrambeigi; Mahsa Khatamnezhad; Siamak Asri-Rezaei; Bahram Dalir-Naghadeh; Shahram Javadi; Navideh Mirzakhani

Volume 12, Issue 2 , June 2021, , Pages 175-183

  The present study was conducted to evaluate the effects of different doses of haloperidol (HP) on induction of oxidative stress in blood and liver cell degeneration in comparison with influences of HP pre-treatment on inflammatory process induced by intraperitoneal (IP) administration of lipopolysaccharide ...  Read More

Caffeic acid protects mice pancreatic islets from oxidative stress induced by multi-walled carbon nanotubes (MWCNTs)

Akram Ahangarpour; Soheila Alboghobeish; Ali Akbar Oroojan; Mohammad Amin Dehghani

Volume 12, Issue 1 , March 2021, , Pages 77-85

  Increasing applications of carbon nanotubes (CNTs) indicate the necessity to examine their toxicity. According to previous studies, CNTs caused oxidative stress that impaired β-cell functions and reduced insulin secretion. Our previous study indicated that single-walled carbon nanotubes (SWCNTs) ...  Read More

Attenuating effects of Mangifera indica leaves ethanolic extract against acetamiprid induced reproductive toxicity in male guinea pigs

Arthénice Jemima Nounamo Guiekep; Augustave Kenfack; Ferdinand Ngoula; Bertin Narcisse Vemo; Kenmeuhe Sidje Nguemmeugne; Etienne Pamo Tedonkeng

Volume 10, Issue 3 , September 2019, , Pages 187-192

  Acetamiprid (ACP) belonging to the neonicotinoid family used against wide array of pests in agriculture and domestic purposes. In this study, we evaluated the attenuating effects of ethanolic extract of Mangifera indica leaves (EEMI) in averting reproductive toxicity caused by ACP in male guinea pigs. ...  Read More

Stem Cells
DNA damage in dental pulp mesenchymal stem cells: An in vitro study

Jaime Sardá Aramburú Junior; Tiago Luis Eilers Treichel; Saulo Tadeu Lemos Pinto Filho; Sergio Alexandre Gerhke; Alencar Kolinski Machado; Francine Carla Cadoná; Ivana Beatrice Mânica da Cruz; Ney Luis Pippi

Volume 9, Issue 4 , December 2018, , Pages 293-299

  The aim of this study was to evaluate the potential use of a DNA comet assay, DNA fragmentation fluorimetric assay and reactive oxygen species levels as potential biomarkers of genome conditions of dental pulp stem cells (DPSCs) isolated from dog canine teeth. Mesenchymal stem cells were isolated from ...  Read More

Clinical Pathology
Comparative study of the protective effects of chicken embryo amniotic fluid, vitamin C and coenzyme Q10 on cyclophosphamide-induced oxidative stress in mice ovaries

Alireza Kabirian; Rooz Ali Batavani; Siamak Asri-Rezaei; Ali Soleimanzadeh

Volume 9, Issue 3 , September 2018, , Pages 217-224

  Cyclophosphamide is a chemotherapy drug for the treatment of cancer. Chicken embryo amniotic fluid, vitamin C and coenzyme Q10 have anti-oxidant properties. Total of 70 adult female mice were selected and divided into seven groups. The first group that received 2 ml kg-1 of inactivated amniotic fluid ...  Read More

Effects of bisphenol-S low concentrations on oxidative stress status and in vitro fertilization potential in mature female mice

Alireza Nourian; Ali Soleimanzadeh; Ali Shalizar Jalali; Gholamreza Najafi

Volume 8, Issue 4 , December 2017, , Pages 341-345

  Bisphenol-S (BPS) is a new bisphenol-A substitute widely used in many plastic products. Bisphenol-A as a main member of bisphenol family has been known as an endocrine system disrupter chemical compound. Like other members of bisphenol family, there is public health concern about the toxic effects of ...  Read More

Ameliorative effects of Achillea millefolium inflorescences alcoholic extract on nicotine-induced reproductive toxicity in male rat: Apoptotic and biochemical evidences

Ameneh Hasanzadeh Khosh; Shapour Hasanzadeh; Ali Shalizar Jalali

Volume 8, Issue 2 , June 2017, , Pages 97-104

  Nicotine (NIC) adversely influences male reproductive system. Achillea millefolium (Achm) as a medicinal plant is highly regarded for its antioxidant and anti-inflammatory properties. The present study was conducted to assess whether Achminflorescences alcoholic extract could serve as a protective agent ...  Read More

Clinical Pathology
Fructooligosaccharide raftilose reduces the mycophenolate mofetil-induced complications: Hematological and biochemical alterations

Hadi Cheraghi; Zohreh Khaki; Hassan Malekinejad; Farhang Sasani

Volume 6, Issue 4 , December 2015, , Pages 319-326

  Mycophenolate mofetil (MMF) is a selective inhibitor of Inosine-5′-monophosphate dehydrogenase. Gastrointestinal (GI) disturbances in immature ones are reported for MMF-induced compilations, which in the case of occurrence dose reduction is required. Thus, in the present study, the fructooligosaccharide ...  Read More

Food Hygiene
Protective role of grape seed proanthocyanidin antioxidant properties on heart of streptozotocin-induced diabetic rats

Esrafil Mansouri; Layasadat Khorsandi; Amin Abdollahzade Fard

Volume 6, Issue 2 , June 2015, , Pages 119-124

  Grape seed proanthocyanidin (GSP) bears a very powerful antioxidant effects. Studies demonstrated that proanthocyanidins protect against free radicals mediated cardiovascular and renal disorders. The present study was designed to assess the effect of GSP on the heart of diabetic rats. Forty rats were ...  Read More

Clinical, laboratory and pathological findings in sub-acute monensin intoxication in goats

Mahdi Deljou; Mohammad Reza Aslani; Mehrdad Mohri; Ahmad Reza Movassaghi; Mohammad Heidarpour

Volume 5, Issue 3 , July 2014, , Pages 161-167

  Toxic effects of monensin, a polyether antibiotic mainly used as a coccidiostat, have been described in a wide range of animals. The present study was performed to investigate the toxic effects of monensin in goats. Seven adult goats were administered sodium monensin, 13.5 mg kg-1, daily for five consecutive ...  Read More

Adverse effects of long-time exposure to formaldehyde vapour on testicular tissue and sperm parameters in rats

Mazdak Razi; Hassan Malekinejad; Reza Sayrafi; Mohammad Reza Hosseinchi; Sajad Feyzi; Seyed Mehdi Moshtagion; Hamed Janbaz

Volume 4, Issue 4 , December 2013, , Pages 213-219

  Formalin is widely used in industry and in medicine (as tissue fixative and disinfectant).It contains reactive molecules which have been known for its cytotoxic effects. To evaluate the effect of formalin exposure on the testicular tissue and sperm parameter from neonatal period through physical and ...  Read More

Effect of Camel Milk on Oxidative Stresses in Experimentally Induced Diabetic Rabbits

El-Said El-Sherbini El-Said; Gehad Ramadan El-Sayed; Esraa Tantawy

Volume 1, Issue 1 , June 2010, , Pages 30-43

  Camel milk has an importance in the treatment of diabetes. It has been shown that the patients who drink camel milk daily, their need to insulin decrease. Therefore, this study aimed to investigate the effect of camel milk in comparison with insulin treatment in experimentally-induced diabetes. This ...  Read More